Results 101 to 110 of about 10,856 (192)

Cryptogenic ischemic stroke in cardiac transthyretin amyloidosis and sinus rhythm: a case report

Frontiers in Cardiovascular Medicine
Cardiac amyloidosis is a group of diseases characterized by the deposition of amyloid fibers in cardiac tissue. Two forms are mainly reported: light chain (AL) and transthyretin (ATTR) amyloidosis.
Angela Napolitano, Serena Toffanin, Cristiana Bulato, Elena Campello, Paolo Simioni, Luca Spiezia   +5 more
doaj   +1 more source

Role of FibroScan in evaluating hepatic involvement in systemic amyloidosis: a single‐centre prospective pilot study

Internal Medicine Journal, EarlyView.
Abstract Background Amyloidosis encompasses a group of diseases characterised by extracellular deposition of misfolded protein fibrils, potentially leading to organ dysfunction. Liver involvement occurs via direct amyloid infiltration, common in immunoglobulin light chain (AL) amyloidosis, or congestive hepatopathy, more typical in transthyretin (ATTR)
M Tang, N Vootukuru, J Tjahyadi, D Clayton Chubb, H Jina, SB Ting, S Bloom, R Sawhney, S Gibbs, O. Niewiadomski   +9 more
wiley   +1 more source

Retinol and retinol-binding protein stabilize transthyretin via formation of retinol transport complex.

, 2010
Transthyretin (TTR) is a plasma hormone carrier protein associated with hereditary and senile forms of systemic amyloid disease, wherein slow tetramer disassembly is thought to be an obligatory step. Plasma transport of retinol is carried out exclusively
Robinson, Carol V, Carol V. Robinson, Stéphanie Deroo, Deroo, Stéphanie, Hyung, Suk-Joon, Suk-Joon Hyung   +5 more
core   +1 more source

Temporal Trends of Wild-Type Transthyretin Amyloid Cardiomyopathy in the Transthyretin Amyloidosis Outcomes Survey

, 2021
Background: Transthyretin amyloid cardiomyopathy results from the accumulation of wild-type (ATTRwt) or variant (ATTRv) transthyretin amyloid fibrils in the myocardium.
Steidley D., Plante-Bordeneuve V., Costello J. G., Slosky D., Mueller C., Sarswat N., Garcia-Pavia P., Murali S., Wixner J., Polydefkis M., Siu A., Sekijima Y., Witteles R., Gess B., Marburger T., Cirami C. L., Hummel S., Emdin M., Lenihan D., Jacoby D., Kristen A. V., LoRusso S., Nativi-Nicolau J., Lairez O., Luigetti M., Adams D., Maurer M. S., Gonzalez Duarte Briseno M. A., Tauras J., Waddington-Cruz M., Moreno J. G., Azevedo O., Hoffman J., Rapezzi C., Schmidt H., Luo J., Drachman B., Nienhuis H., Moelgaard H., Dispenzieri A., Shah S., Cotts W., Gottlieb S., Barroso F. A., Van Cleemput J., Zivkovic S., Jeon E. -S., Ralph J., Amass L., Ventura H., Grogan M., Quan D., Vita G., Tallaj J., Parman Y., Inamo J., Fine N., Campistol Plana J. M., Yamashita T., Chapman D.   +59 more
core   +1 more source

Palinacousis in amyloidosis: exploring the hallucinatory phenomenon in brain pathology—a case report

Journal of Medical Case Reports
Background Hereditary transthyretin amyloidosis, caused by transthyretin gene mutations, progresses with systemic impact and often presents peripheral neuropathy.
João Martins-Correia, Luísa Sousa
doaj   +1 more source

Feasibility, Safety, and Efficacy of Pulsed Field Ablation for Ventricular Arrhythmias: Insights From a Large Health System Registry in the United States

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging non‐thermal ablation modality with proven safety in atrial arrhythmia ablation. However, data on its performance for ventricular arrhythmias (VA) remain limited. Objective To evaluate the feasibility, safety, and efficacy of PFA for complex VA in a multicenter real‐world US registry ...
Narut Prasitlumkum, Juan F. Rodriguez‐Riascos, Hema Vemulapalli, Aakash Somappa, Camilo A. Estrada‐Vargas, Olubadewa A. Fatunde, Carlos A. Rojas, Poojan Prajapati, Keerthika Vijayakumar, Suraj Kapa, Duy Nguyen, Samuel Asirvatham, Malini Madhavan, Christopher McLeod, Hicham Z. El Masry, Abhishek J. Deshmukh, Danesh K. Kella, Ammar M. Killu, Siva K. Mulpuru, Mayank Sardana, Luis R. Scott, Alan M. Sugrue, Komandoor Srivathsan   +22 more
wiley   +1 more source

Scavenger receptor class B member 1 independent uptake of transthyretin by cultured hepatocytes is regulated by high density lipoprotein

, 2019
Thyroid hormone (thyroxine, T4) is essential for the normal function of all cell types and is carried in serum bound to several proteins including transthyretin.
Richard, Kerry, d'Emden, Michael C., Landers, Kelly A.   +2 more
core   +1 more source

Real-life experience with inotersen at CEPARM, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro

Arquivos de Neuro-Psiquiatria
Background Hereditary transthyretin amyloidosis (ATTRv) is an inherited, progressive, and fatal disease still largely underdiagnosed. Mutations in the transthyretin (TTR) gene cause the TTR protein to destabilize, misfold, aggregate, and ...
Moises Dias, Luiz Felipe Pinto, Marcus Vinícius Pinto, Renata Gervais, Paula Accioli, Gabriela Amorim, Mariana Guedes, Carlos Perez Gomes, Roberto Coury Pedrosa, Márcia Waddington-Cruz   +9 more
doaj   +1 more source

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

Transthyretin is not necessary for thyroid hormone metabolism in conditions of increased hormone demand [PDF]

, 2005
Thyroid hormones circulate in blood mainly bound to plasma proteins. Transthyretin is the major thyroxine plasma carrier in mice. Studies in transthyretin-null mice revealed that the absence of transthyretin results in euthyroid hypothyroxinemia and ...
Morreale de Escobar, Gabriella, Sousa, J. C., Saraiva, M. J., Saraiva, Maria João, Oliveira, Pedro, Palha, Joana Almeida, Sousa, João Carlos, de Escobar, G. Morreale, Oliveira, P.   +8 more
core   +1 more source