Results 151 to 160 of about 61,872 (307)

Influence of Nanoparticle Size and Shape on Oligomer Formation of an Amyloidogenic Peptide [PDF]

, 2011
Understanding the influence of macromolecular crowding and nanoparticles on the formation of in-register $\beta$-sheets, the primary structural component of amyloid fibrils, is a first step towards describing \emph{in vivo} protein aggregation and ...
Allen M. P., Asakura S., Auer S., Batra J., Behe M., Bernard R. Brooks, Brooks B. R., Chan J. C. C., Cheung M. S., Chiti F., Colvin V. L., Colvin V. L., Cotter M. A., Cunha S., D. Thirumalai, del Álamao M., Dhar A., Dima R. I., Edward P. O’Brien, Elcock A. H., Fleer G. J., Flory P. J., Hall D., Hofrichter J., Jaroniec C. P., Jaroniec C. P., John. E. Straub, Lazaridis T., Lindner R. A., Linse S., Magno A., McGuffee S. R., Nelson R., Nelson R., Nguyen P. H., Petty S. A., Pierotti R. A., Rohrig U. F., Ross P. D., Sacchettini J. C., Schreiber G., Shaw M. R., Stagg L., Straub J. E., Tarus B., Tellam R. L., Tycko R., Walter H., Wu C., Zhou H. X., Zimmerman S. B.   +50 more
core   +1 more source

A new therapy for transthyretin amyloidosis, no longer an orphan condition [PDF]

, 2020
Candida Cristina Quarta, Anna Laura Tinuper, Agnese Milandri, Christian Gagliardi, Giuseppe Caponeti, Claudio Rapezzi   +5 more
openalex   +1 more source

Heart failure with preserved ejection fraction in cancer patients and survivors. A scientific statement of the Heart Failure Association of the ESC and the ESC Council of Cardio‐Oncology

European Journal of Heart Failure, EarlyView.
Specific characteristics of HFpEF universal definition in cancer patients. Abstract Heart failure with preserved ejection fraction (HFpEF) is increasingly recognized in cancer patients and survivors, yet it remains underdiagnosed and its epidemiology largely unknown.
Kalliopi Keramida, Teresa Lopez‐Fernandez, Markus S. Anker, Mark C. Petrie, Pietro Ameri, Lisa J. Anderson, Jutta Bergler‐Klein, Anita Deswal, Dimitrios Farmakis, Borja Ibañez, Carolyn S.P. Lam, Ninian N. Lang, Alexander R. Lyon, Mariana Mirabel, Brenda Moura, Walter J. Paulus, Amina Rakisheva, Gianluigi Savarese, Michele Senni, Carlo Gabriele Tocchetti, Marco Metra, Gerasimos Filippatos   +21 more
wiley   +1 more source

Usefulness of automatic assessment for longitudinal strain to diagnose wild-type transthyretin amyloid cardiomyopathy

, 2023
Hiroki Usuku, Eiichiro Yamamoto, Daisuke Sueta, Kanako Imamura, Fumi Oike, Kyohei Marume, Masanobu Ishii, Shinsuke Hanatani, Yuichiro Arima, Seiji Takashio, Seitaro Oda, Hiroaki Kawano, Mitsuharu Ueda, Hirotaka Matsui, Kenichi Tsujita   +14 more
openalex   +1 more source

Inotersen: new promise for the treatment of hereditary transthyretin amyloidosis

Drug Design, Development and Therapy, 2019
Veena Mathew,1 Annabel K Wang1,2 1Department of Neurology, UCI ALS and Neuromuscular Center, University of California, Irvine, Orange, CA, USA; 2Neurology Section, Tibor Rubin VA Medical Center, Long Beach, CA, USA Abstract: Hereditary transthyretin ...
Mathew V, Wang AK
doaj  

Proteomic Analysis of Serum in Cardiac Transthyretin Amyloidosis: Diagnostic and Prognostic Implications for Biomarker Discovery

Biomedicines
Background/Objectives: Having serum biomarkers available for cardiac transthyretin amyloidosis (ATTR-CA) would be beneficial for diagnosis and prognosis. This study aimed to identify potential ATTR-CA biomarkers through proteomic analysis.
Joanna Waś, Monika Gawor-Prokopczyk, Agnieszka Sioma, Rafał Szewczyk, Aleksandra Pel, Jolanta Krzysztoń-Russjan, Magdalena Niedolistek, Dorota Sokołowska, Jacek Grzybowski, Łukasz Mazurkiewicz   +9 more
doaj   +1 more source

FGF2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus cell behaviour [PDF]

, 2008
Background Although fibroblast growth factor (Fgf) signalling plays crucial roles in several developing and mature tissues, little information is currently available on expression of Fgf2 during early choroid plexus development and whether Fgf2 directly ...
Ferretti, P., Greenwood, S., Swetloff, A., Terasaki, T., Wade, A.   +4 more
core   +3 more sources

Clinical phenotype and prognosis of real‐world patients with wild‐type transthyretin amyloid cardiomyopathy treated with tafamidis

European Journal of Heart Failure, EarlyView.
Aims Tafamidis reshaped the treatment paradigm in transthyretin amyloid cardiomyopathy (ATTR‐CM) based on a phase‐3 randomized controlled trial, but real‐world data on its use remain limited. This study aimed to assess in a large, contemporary, real‐world cohort of patients with wild‐type ATTR‐CM (ATTRwt‐CM) (i) the clinical phenotype of patients ...
Aldostefano Porcari, Paolo Milani, Simone Longhi, Francesco Cappelli, Fabio Vagnarelli, Alberto Aimo, Alberto Cipriani, Elisa Gardini, Stefania Marazia, Emanuele Monda, Giacomo Tini, Beatrice Musumeci, Matteo Serenelli, Anna Cantone, Carla Lofiego, Marco Marini, Giuseppe Vergaro, Grazia Foti, Francesco Musca, Daniela Tomasoni, Giacomo Bonacchi, Federica Colio, Giulio Sinigiani, Laura De Michieli, Francesca Sturdà, Marco Pozzan, Piero Gentile, Samuela Carigi, Michela Bartolotti, Giuseppe Sena, Irene Ruotolo, Giuseppe Damiano Sanna, Margherita Zanoletti, Marco Canepa, Massimo Di Marco, Emilia D'Elia, Gianluca Di Bella, Mauro Driussi, Massimo Imazio, Federico Perfetto, Elena Biagini, Giuseppe Limongelli, Marco Metra, Michele Emdin, Giampaolo Merlini, Stefano Perlini, Marco Merlo, Giovanni Palladini, Gianfranco Sinagra   +48 more
wiley   +1 more source

P.041 Characteristics of carpal tunnel syndrome in wild-type transthyretin amyloidosis [PDF]

, 2022
A Russell, S Khayambashi, NM Fine, S Chhibber, C Hahn   +4 more
openalex   +1 more source

Artificial intelligence‐based echocardiographic assessment for monitoring disease progression in transthyretin cardiac amyloidosis

European Journal of Heart Failure, EarlyView.
Artificial intelligence (AI)‐based estimation of stroke volume for risk prediction in amyloid transthyretin cardiomyopathy (ATTR‐CM). ATTRv, hereditary transthyretin amyloidosis; ATTRwt, wild‐type transthyretin amyloidosis; CI, confidence interval; HR, hazard ratio; IQR, interquartile range; LVOT‐VTI, left ventricular outflow tract velocity‐time ...
Lucia Venneri, Alberto Aimo, Aldostefano Porcari, Irem Sezer, Adam Ioannou, Awais Sheikh, Josephine Mansell, Yousuf Razvi, Surabhi Bhaskar Iyer, Ana Martinez‐Naharro, Francesco Bandera, Sze Chi Lim, Matthew Frost, Justin Ezekowitz, Carolyn S.P. Lam, William Moody, Carol Whelan, Helen Lachmann, Ashutosh Wechelakar, Michele Emdin, Philip N. Hawkins, Scott David Solomon, Julian D. Gillmore, Marianna Fontana   +23 more
wiley   +1 more source