Results 161 to 170 of about 60,909 (346)

Palinacousis in amyloidosis: exploring the hallucinatory phenomenon in brain pathology—a case report

Journal of Medical Case Reports
Background Hereditary transthyretin amyloidosis, caused by transthyretin gene mutations, progresses with systemic impact and often presents peripheral neuropathy.
João Martins-Correia, Luísa Sousa
doaj   +1 more source

Blood-brain-barriers in aging and in Alzheimer's disease [PDF]

, 2013
The aging process correlates with a progressive failure in the normal cellular and organ functioning; these alterations are aggravated in Alzheimer's disease (AD).
Marques, Fernanda, Palha, Joana Almeida, Sousa, João Carlos, Sousa, Nuno   +3 more
core   +1 more source

Long‐term efficacy of tafamidis in patients with transthyretin amyloid cardiomyopathy by National Amyloidosis Centre stage

European Journal of Heart Failure, EarlyView.
Long‐term efficacy of tafamidis in patients with ATTR‐CM in ATTR‐ACT and its LTE by NAC stage at ATTR‐ACT baseline. ATTR‐ACT, Tafamidis in Transthyretin Cardiomyopathy Clinical Trial; ATTR‐CM, transthyretin amyloid cardiomyopathy; NAC, National Amyloidosis Centre.
Thibaud Damy, Rong Wang, Mathew S. Maurer, Julian D. Gillmore, Marianna Fontana   +4 more
wiley   +1 more source

Is Transthyretin a Regulator of Ubc9 SUMOylation?

PLOS ONE, 2016
Ageing and mutations of transthyretin (TTR), the thyroid hormones and retinol transporting protein lead to amyloidosis by destabilizing the structure of TTR. Because protein structure is regulated through posttranslational modifications, we investigated the Small Ubiquitin-like Modifier (SUMO)ylation of TTR.
Elżbieta Wieczorek, Sylwia Kędracka–Krok, Katarzyna Sołtys, Urszula Jankowska, Rafał Hołubowicz, Justyna Seliga, Andrzej Ożyhar   +6 more
openaire   +6 more sources

Inotersen: new promise for the treatment of hereditary transthyretin amyloidosis

Drug Design, Development and Therapy, 2019
Veena Mathew,1 Annabel K Wang1,2 1Department of Neurology, UCI ALS and Neuromuscular Center, University of California, Irvine, Orange, CA, USA; 2Neurology Section, Tibor Rubin VA Medical Center, Long Beach, CA, USA Abstract: Hereditary transthyretin ...
Mathew V, Wang AK
doaj  

Proteomic Analysis of Serum in Cardiac Transthyretin Amyloidosis: Diagnostic and Prognostic Implications for Biomarker Discovery

Biomedicines
Background/Objectives: Having serum biomarkers available for cardiac transthyretin amyloidosis (ATTR-CA) would be beneficial for diagnosis and prognosis. This study aimed to identify potential ATTR-CA biomarkers through proteomic analysis.
Joanna Waś, Monika Gawor-Prokopczyk, Agnieszka Sioma, Rafał Szewczyk, Aleksandra Pel, Jolanta Krzysztoń-Russjan, Magdalena Niedolistek, Dorota Sokołowska, Jacek Grzybowski, Łukasz Mazurkiewicz   +9 more
doaj   +1 more source

FGF2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus cell behaviour [PDF]

, 2008
Background Although fibroblast growth factor (Fgf) signalling plays crucial roles in several developing and mature tissues, little information is currently available on expression of Fgf2 during early choroid plexus development and whether Fgf2 directly ...
Ferretti, P., Greenwood, S., Swetloff, A., Terasaki, T., Wade, A.   +4 more
core   +3 more sources

Heart failure with preserved ejection fraction in cancer patients and survivors. A scientific statement of the Heart Failure Association of the ESC and the ESC Council of Cardio‐Oncology

European Journal of Heart Failure, EarlyView.
Specific characteristics of HFpEF universal definition in cancer patients. Abstract Heart failure with preserved ejection fraction (HFpEF) is increasingly recognized in cancer patients and survivors, yet it remains underdiagnosed and its epidemiology largely unknown.
Kalliopi Keramida, Teresa Lopez‐Fernandez, Markus S. Anker, Mark C. Petrie, Pietro Ameri, Lisa J. Anderson, Jutta Bergler‐Klein, Anita Deswal, Dimitrios Farmakis, Borja Ibañez, Carolyn S.P. Lam, Ninian N. Lang, Alexander R. Lyon, Mariana Mirabel, Brenda Moura, Walter J. Paulus, Amina Rakisheva, Gianluigi Savarese, Michele Senni, Carlo Gabriele Tocchetti, Marco Metra, Gerasimos Filippatos   +21 more
wiley   +1 more source

Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal. [PDF]

, 2019
Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying ...
Christian, Parul, Cole, Robert N, Eroglu, Abdulkerim, Groopman, John, Lee, Sun Eun, Schulze, Kerry, Stewart, Christine P, West, Keith P, Wu, Lee S-F, Yager, James D   +9 more
core  

Familial ATTR amyloidosis: microalbuminuria as a predictor of symptomatic disease and clinical nephropathy [PDF]

, 2003
Familial ATTR amyloidosis: microalbuminuria as a predictor of symptomatic disease and clinical nephropathy. Lobato L, Beirão I, Silva M, Bravo F, Silvestre F, Guimarães S, Sousa A, Noël LH, Sequeiros J.
Beirao, I., Bravo, F., Guimaraes, S., Lobato, L., Noel, LH., Sequeiros, J., Silva, M., Silvestre, F., Sousa, A.   +8 more
core   +1 more source