Results 201 to 210 of about 60,909 (346)

Amyloidosis for the Gastroenterologist: A Comprehensive Systematic Review of Diagnosis and Management of Gastrointestinal Manifestations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang, Theng Yi Tay, Simon Gibbs, Ola Niewiadomski   +3 more
wiley   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

Experimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene, Anita M. van den Hoek, Roeland Hanemaaijer, Lars Verschuren, Jelle C. B. C. de Jong   +4 more
wiley   +1 more source

Acoramidis in Transthyretin Amyloid Cardiomyopathy

New England Journal of Medicine
To the Editor: In a phase 3 trial of acoramidis for transthyretin amyloid cardiomyopathy, Gillmore et al. (Jan. 11 issue)(1) used the Finkelstein-Schoenfeld test to assess the hierarchical composite primary outcome. They expressed the treatment effect as a win ratio, thereby following the initial presentation of the analysis of a prioritized outcome.(2)
VERBEECK, Johan, De Backer, Mickael, BUYSE, Marc   +2 more
openaire   +5 more sources

Association between rat decompression sickness resistance, transthyretin single nucleotide polymorphism, and expression: A pilot study

Physiological Reports
Decompression sickness (DCS) is a systemic syndrome that can occur after an environmental pressure reduction. Previously, we showed that the plasmatic tetrameric form of transthyretin (TTR) nearly disappeared in rats suffering DCS but not in asymptomatic
J. Orsat, A. Guernec, C. Le Maréchal, V. Pichereau, F. Guerrero   +4 more
doaj   +1 more source

The Tetrameric Protein Transthyretin Dissociates to a Non-native Monomer in Solution [PDF]

, 1999
Alexandre Quintas, Maria João Saraiva, Rui M. M. Brito   +2 more
openalex   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Citoszkeletális fehérjék szerkezete, dinamikája, mechanikája és kölcsönhatásai: egyedi molekuláktól szupramolekuláris rendszerekig = Structure, dynamics, mechanics and interactions of cytoskeletal proteins: from single molecules to supramolecular systems [PDF]

, 2013
Pályázatunkban a citoszkeletális fehérjék szerkezetét, dinamikáját, mechanikáját és kölcsönhatásait vizsgáltuk elsősorban a harántcsíkolt izom különböző molekuláris rendszerein.
Grama, László, Huber, Tamás, Karsai, Árpád, Kellermayer, Miklós Sándor Zoltán, Kengyel, András, Kiss, Balázs, Murvai, Csilla Ünige, Mártonfalvi, Zsolt, Nagy, Attila, Szatmári, Dávid Zoltán   +9 more
core  

Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics

Alimentary Pharmacology &Therapeutics, Volume 62, Issue 9, Page 901-919, November 2025.
Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen, Henriette Ytting, Annelaura Bach Nielsen, Mikkel Parsberg Werge, Elias Badal Rashu, Liv Eline Hetland, Mira Thing, Puria Nabilou, Johan Burisch, Anders Ellekær Junker, Lise Hobolth, Christian Mortensen, Flemming Tofteng, Flemming Bendtsen, Søren Møller, Mogens Vyberg, Reza Rafiolsadat Serizawa, Marie Winther‐Sørensen, Jesper Sloth Kellemann, Lise Lotte Gluud, Nicolai Jacob Wewer Albrechtsen   +20 more
wiley   +1 more source

Associations of Left Atrial Volume Index to Left Ventricular Ejection Fraction Ratio with Clinical Outcomes in Transthyretin Cardiac Amyloidosis

Journal of Cardiovascular Development and Disease
Background: Transthyretin amyloid cardiomyopathy (ATTR-CM) affects all cardiac chambers to cause left ventricular (LV) deformation as well as left atrial (LA) remodeling and functional impairment.
Yeabsra K. Aleligne, Machelle D. Wilson, Martin Cadeiras, Michael Gibson, Shirin Jimenez, Stella Yala, Pablo E. Acevedo, David A. Liem, Julie T. Bidwell, Imo A. Ebong   +9 more
doaj   +1 more source

Early destructive spondyloarthropathy from combined 2-microglobulin and transthyretin Met30 amyloidosis in a dialysed patient [PDF]

, 1998
Idalina Beirão, Luísa Lobato, S. Guimaraes, Pedro Cardoso, Paulo Costa, Teresa Coelho, Guilherme Rocha, S. Guimaraes   +7 more
openalex   +1 more source