Results 111 to 120 of about 7,937 (220)

Clinical case of hereditary transthyretin amyloidosis [PDF]

Българска кардиология
Transthyretin amyloidosis (ATTR) is a systemic disease characterized by the deposition of amyloid fi brils in various tissues, leading to progressive neurological manifestations and the development of cardiomyopathy, necessitating timely ...
N. Spasova, E. Kinova, R. Savova, K. Genova, M. Garcheva, A. Goudev   +5 more
doaj   +3 more sources

Natural history and outcome in systemic AA amyloidosis [PDF]

, 2007
BACKGROUND:Deposition of amyloid fibrils derived from circulating acute-phase reactant serum amyloid A protein (SAA) causes systemic AA amyloidosis, a serious complication of many chronic inflammatory disorders.
Gallimore, JR, Gilbertson, JA, Gillmore, JD, Goodman, HJB, Hawkins, PN, Lachmann, HJ, Sabin, CA   +6 more
core   +1 more source

Diagnosis and Treatment of Hereditary Transthyretin Amyloidosis (hATTR) Polyneuropathy: Current Perspectives on Improving Patient Care

Therapeutics and Clinical Risk Management, 2020
Marco Luigetti,1,2 Angela Romano,2 Andrea Di Paolantonio,2 Giulia Bisogni,3 Mario Sabatelli2,3 1Neurology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; 2Università Cattolica del Sacro Cuore, Rome, Italy; 3Centro ...
Luigetti M, Romano A, Di Paolantonio A, Bisogni G, Sabatelli M   +4 more
doaj  

Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease [PDF]

, 2015
Transthyretin amyloidosis is a conformational pathology characterized by the extracellular formation of amyloid deposits and the progressive impairment of the peripheral nervous system.
Barroso, E, Coelho, A, Cordeiro, C, Costa, G, Ferreira, A, Gilberto, S, Gomes, R, Mateus, E, Ponces Freire, A, Ribeiro, R, Ribeiro-Silva, C   +10 more
core  

Infertility and hypergonadotropic hypogonadism as first evidence of hereditary apolipoprotein A-I amyloidosis [PDF]

, 2007
Purpose: We report that primary infertility and hypergonadotropic hypogonadism in young patients may be caused by testicular amyloidosis and it is associated with the presence of a mutation in the apoA-I gene, resulting in the replacement of proline for ...
BIASI L, F. SCOLARI, GREGORINI G, MARTINI PR, MERLINI G, OBICI L, SCALVINI T, TARDANICO R   +7 more
core   +1 more source

Effect of catheter ablation with vein of Marshall ethanol infusion for perimitral flutter in a patient with senile transthyretin cardiac amyloidosis: a case report

Frontiers in Cardiovascular Medicine
BackgroundSenile transthyretin cardiac amyloidosis (AL) is an underdiagnosed infiltrative cardiomyopathy causing heart failure symptoms in elderly patients.
Simon Fitouchi, Mickael Ohana, Thomas Cardi, Laurence Jesel, Laurence Jesel, Halim Marzak, Halim Marzak   +6 more
doaj   +1 more source

Proteomic Analysis of Serum in Cardiac Transthyretin Amyloidosis: Diagnostic and Prognostic Implications for Biomarker Discovery

Biomedicines
Background/Objectives: Having serum biomarkers available for cardiac transthyretin amyloidosis (ATTR-CA) would be beneficial for diagnosis and prognosis. This study aimed to identify potential ATTR-CA biomarkers through proteomic analysis.
Joanna Waś, Monika Gawor-Prokopczyk, Agnieszka Sioma, Rafał Szewczyk, Aleksandra Pel, Jolanta Krzysztoń-Russjan, Magdalena Niedolistek, Dorota Sokołowska, Jacek Grzybowski, Łukasz Mazurkiewicz   +9 more
doaj   +1 more source

Advancing diagnostics and therapy in transthyretin amyloid cardiomyopathy. [PDF]

ESC Heart Fail
Holcman K, Tkaczyszyn M.
europepmc   +5 more sources

Cardiac amyloidosis

Annales Academiae Medicae Silesiensis
Amyloidosis is a rare disease characterized by an abnormal accumulation of the amyloid protein in tissues. Amyloidosis can be divided into two main subtypes: transthyretin amyloidosis (ATTR-CA) and immunoglobulin light chain amyloidosis (AL-CA ...
Magdalena Balwierz, Bartosz Gruchlik, Katarzyna Mizia-Stec   +2 more
doaj   +1 more source

Neuromuscular manifestations of wild type transthyretin amyloidosis: a review and single center’s experience

Frontiers in Cardiovascular Medicine
Transthyretin amyloidosis (ATTR) is a condition defined by accumulation of insoluble transthyretin amyloid deposits in multiple organs, especially in the peripheral nerve and heart muscle.
Sasha A. Živković, Sasha A. Živković, Sasha A. Živković, David Lacomis, David Lacomis, Prem Soman, Prem Soman   +6 more
doaj   +1 more source