Aims Recognition of transthyretin amyloid cardiomyopathy is increasing due to advances in cardiac imaging and diagnostic strategies, but questions remain regarding disease frequency and characteristics.
Francesco Cappelli +2 more
exaly +7 more sources
3 Discordant Extracardiac Amyloid Proteins Highlighting Bystander Deposition in a Case of Light-Chain Amyloid Cardiomyopathy [PDF]
Background: Accurate differentiation of immunoglobulin light-chain (AL) from transthyretin (ATTR) amyloid cardiomyopathy is critical, as misclassification may delay appropriate therapy and worsen outcomes.
Roxanne Coderre, MD +9 more
doaj +2 more sources
Coexistence of Hypertrophic Cardiomyopathy and Hereditary Transthyretin Amyloid Cardiomyopathy [PDF]
Background: Left ventricular wall thickening may result from disease such as hypertrophic cardiomyopathy (HCM) or infiltrative cardiomyopathies such as transthyretin amyloidosis (ATTR).
Roxanne Coderre, MD +9 more
doaj +2 more sources
Machine Learning of Echocardiographic Left Ventricular Myocardial Radiomics for Identification of Transthyretin Amyloid Cardiomyopathy [PDF]
Background: Transthyretin amyloid cardiomyopathy (ATTR-CM) is an important cause of heart failure (HF) with increased left ventricular (LV) wall thickness that can be challenging to distinguish from other LV hypertrophic processes.
Ali A. Elzieny, MD, MSc +11 more
doaj +2 more sources
Diagnostic Trends and Geographic Health Care Disparities Among Patients With Transthyretin Amyloid Cardiomyopathy [PDF]
Background Transthyretin amyloid cardiomyopathy (ATTR‐CM) is a rare, life‐threatening form of restrictive cardiomyopathy. Access to cardiology providers and specialized amyloid centers may impact ATTR‐CM diagnosis.
Joshua D. Mitchell +6 more
doaj +2 more sources
Systemic Oxalosis Mimicking Transthyretin Amyloid Cardiomyopathy [PDF]
Background: Technetium-99m pyrophosphate (Tc-99m PYP) scintigraphy is a noninvasive imaging modality in the diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM), though false positive results may result in adverse clinical outcomes.
Bhavya Ancha, MD +9 more
doaj +2 more sources
Pathogenic Characterization of a Novel G47R Transthyretin Mutation in Early‐Onset Amyloid Cardiomyopathy [PDF]
Background Transthyretin amyloid cardiomyopathy is a progressive infiltrative cardiomyopathy driven by the deposition of amyloid fibrils derived from destabilized transthyretin (TTR).
Bo Wang +15 more
doaj +2 more sources
AL-amyloidosis with cardiac involvement. Diagnostic capabilities of non-invasive methods
There are presented the literature data and a description of the clinical course of the disease in isolated/predominant cardiac amyloidosis. Amyloid cardiomyopathy is the most common phenocopy of hypertrophic cardiomyopathy.
Alexandra Ya. Gudkova +13 more
doaj +1 more source
Transthyretin amyloid cardiomyopathy is a treatable but often unrecognized cause of heart failure. We derived and validated a machine learning model based on medical diagnostic codes that identifies heart failure patients at risk for wild-type ...
Ahsan Huda +9 more
doaj +1 more source
A new era in treatment of cardiac amyloidosis: an overview of the Congress of cardiology
Amyloidosis is a group of diseases characterized by accumulation of a protein of a specific fibrillar structure in the interstitium of various organs and tissues.
I. E. Strelkova
doaj +1 more source

