Results 171 to 180 of about 1,227 (255)

Conceptual frameworks, competencies, contents and teaching methods in planetary health education for health students and professionals: a global systematic scoping review. [PDF]

BMC Med Educ
Carrion C, Llamas CA, Safitri ED, Domènech-Panicello C, Downward GS, Findyartini A, Greviana N, Murni IK, Lee SM, Llimós M, Moreno A, O'Brien SL, Ruiz-Mallén I, Soemantri D, Widyahening IS, Ranakusuma RW, Fitriani DY, O'Callaghan-Gordo C.   +17 more
europepmc   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Impact of nursing robotic assisted surgery education on Kirkpatrick's four levels. [PDF]

Front Surg
Cerruto MA, Veronese E, Moretti F, Mansueti N, Azzolini M, Poiesi E, Vezzari N, Vignola E, Gulotta D, Barp A, Veccia A, Porcaro AB, Bertolo RG, Antonelli A, Leardini R, Dal Corso L, Zanolli M.   +16 more
europepmc   +1 more source

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

Advanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma, Huimin Gong, Ran Zhuo, Zaixiao Rao, Yanxi Wan, Mingyang Wang, Zahra Zeinalzadeh, Yuan Gao, Aohan Guan, Xinrun Li, Wanting Chen, Xiliang Wang, Yun Wan, Sihua Zhang, Yuncai Xiao, Qi Huang, Paul R. Langford, Xiangru Wang, Rui Zhou, Rui Luo, Hongbo Zhou, Chengliang Zhu, Hui Jin   +22 more
wiley   +1 more source

Territorial Constraints on Trap-Neuter-Return in Insular Landscapes: Demographic and Ecological Implications of a Conservation-Oriented Policy. [PDF]

Animals (Basel)
Manzanares-Fernández R, Martínez-Campo J, Travieso-Aja MDM, Luzardo OP.   +3 more
europepmc   +1 more source

Systemic Nanomechanical Single‐Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation

Advanced Science, EarlyView.
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku, Jinwon Kwon, Nara Yoon, Hyung Kwon Byeon, Jaemoon Yang   +4 more
wiley   +1 more source

Health Education in the Curriculum of Early Childhood Education in Galicia, Spain: An Analysis of Decree 150/2022. [PDF]

Healthcare (Basel)
Gigirey-Vilar A, Navarro-Patón R, Martínez-Isasi S, Rodríguez-Fernández JE.   +3 more
europepmc   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Tutorial action during the veterinary doctoral program at the Complutense University of Madrid, Spain. [PDF]

Front Vet Sci
Fuertes-Recuero M, De Pablo-Moreno JA, Heras-Molina A, Morón-Elorza P, Encinas Cerezo T.   +4 more
europepmc   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source