Results 151 to 160 of about 36,221 (299)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Learning and assessment strategies to develop specific and transversal competencies for a humanized medical education. [PDF]

Front Physiol, 2023
Tutor AS, Escudero E, Del Nogal Ávila M, Aranda JF, Torres H, Yague JG, Borrego MJ, Muñoz Ú, Sádaba MC, Sánchez-Vera I.   +9 more
europepmc   +1 more source

Guidance on personalised learning and the Cloud [PDF]

, 2016
A short manual for schools who wish to implement personalised ...
Zwartjes, Luc
core  

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

E-Learning for Teachers and Trainers : Innovative Practices, Skills and Competences [PDF]

, 2004
Reproduction is authorised provided the source is acknowledged.Final Published ...
Battezzati, L, Coulon, A, Gray, DE, Mansouri, I, Ryan, M, Walker, R   +5 more
core  

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

The ethics of ICT. Transversal competencies and paradox

Education in the Knowledge Society, 2013
Education systems in the era of new technologies have a revolution in traditional learning processes. For proper implementation of these changes, teachers have to be train in 'new' ethical competencies, which give meaning to the digital skills. This leads to a new way of understanding pedagogy where students gain prominence and autonomy to obtain, for ...
Marta BURGUET, Mª Rosa BUXARRAIS
openaire   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

Co-working Space: Project Based Transversal Competencies

Proceedings of the 2nd International Conference on Learning Innovation, 2018
Ahmad Munjin Nasih, . Sucipto, Heppy Jundan Hendrawan   +2 more
openaire   +1 more source