Results 51 to 60 of about 1,227 (255)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Defining the Industrial and Engineering Management Professional Profile: a longitudinal study based on job advertisements

Production
The engineering professional profiles have been discussed by several branches of the engineering field. On the one hand, this discussion helps to understand the professional practice and contributes to the specification of the competences that are ...
Rui Manuel Lima, Diana Mesquita, Carla Rocha, Mauro Rabelo   +3 more
doaj   +1 more source

CUMULATIVE DEVELOPMENT OF EDUCATIONAL RESEARCH AND INNOVATION COMPETENCES IN THE TRAINING OF PRIMARY AND PRE-SCHOOL EDUCATION TEACHERS [PDF]

Social Sciences and Education Research Review, 2020
The article analyses, from multiple perspectives, the problem of developing the educational research and innovation competences of the future primary and pre-school education teachers, with a view to the integral development of the training dimensions ...
Claudiu Marian Bunăiaşu
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Unlocking potential: exploring the interplay between entrepreneurship and research competence across diverse academic disciplines

Frontiers in Education
This study aims to identify and analyze the self-assessment of entrepreneurship sub-competences among students at Latvian higher education institutions.
Dace Medne, Agnese Lastovska, Gatis Lama, Jana Grava   +3 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Legislative Analysis of Spanish Education: from Content-Based Education to Transversal Competency-Based Education = Análisis Legislativo de la Educación Española: de una Educación Basada en Contenidos a la Educación Basada en Competencias Transversales

Advances in Building Education
La legislación es el eje vertebrador de la política educativa. En función de lo que estipule la normativa educativa se aplicarán unos principios u otros. Este trabajo de investigación emplea un diseño cualitativo, basado en el análisis de contenido de la
Lionel Sánchez-Bolívar, Sergio Escalante-González, Sara Arenas-Carranza, Lindsay Michelle Vázquez   +3 more
doaj   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Formative assessment framework proposal for transversal competencies: Application to analysis and problem-solving competence

Journal of Industrial Engineering and Management, 2018
Purpose: In the last years, there is an increasing interest in the manner that transversal competences (TC) are introduced in the curricula. Transversal competences are generic and relevant skills that students have to develop through the several stages ...
Pedro Gómez-Gasquet, Mª José Verdecho, Raúl Rodriguez-Rodriguez, Juan José Alfaro-Saiz   +3 more
doaj   +1 more source