Results 51 to 60 of about 1,786 (251)

Generative Artificial Intelligence and Transversal Competencies in Higher Education: A Systematic Review

open access: yesApplied System Innovation
Generative AI is an emerging tool in higher education; however, its connection with transversal competencies, as well as their sustainable adoption, remains underexplored.
Angel Deroncele-Acosta   +3 more
doaj   +1 more source

The Development of Soft Skills through Music in Educational Contexts: A Systematic Review

open access: yesEducation Sciences, 2023
Numerous scientific studies confirm that music is a tool to improve and develop interpersonal skills. These skills, such as leadership, teamwork, communication, interpersonal skills, or coordination.
Mario Diz-Otero   +3 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Significance of Educational Methods in Shaping Graduates’ Competencies in Belarus

open access: yesJournal of Teaching and Learning
This paper analyses higher education graduates’ feedback on how teaching-learning methods enhance competencies. The analysis focuses on Belarus and uses data from the Fostering Competencies Development in Belarusian Higher Education (FOSTERC) survey, an
Isidora Navarro-Milla   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Key Professional Competencies for Graduates in the Job Market: An Analysis of Employer Expectations in 2024

open access: yesStudies and Scientific Researches: Economics Edition
This article presents some of the results of a study on the importance that employers attach to some of the professional competencies of university graduates, as well as on the level of satisfaction with graduates' competencies, respectively the need to
Laura Timiras   +4 more
doaj   +1 more source

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