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The Possibility of Forming Transversal Competencies in a Professional and Pedagogical University [PDF]

, 2021
В статье рассматриваются вопросы возможного формирования трансверсальных компетенций у студентов профессионально-педагогического вуза. Представлен анализ понятия трансверсальная компетенция, определены ее компоненты.
Ильина, Н. Н., Ilina, N. N., Шульц, О. Н., Shults, O. N.   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Towards new educational standards for aircraft maintenance: analysing transversal competencies on industry safety priorities and assessment challenges

Cogent Education
The aviation industry is one of the most regulated industries in the world; safety is its overriding objective. In Europe, aviation maintenance training regulations rely on time-based technical experience and theoretical multiple-choice exams for a basic
Lydia Kes, Gillian N. Saunders-Smits, Marcus M. Specht   +2 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

STEAM-Learning to Mars: Students’ Ideas of Space Research

Education Sciences, 2021
Multidisciplinarity and the enrichment of science and mathematics education toward the so-called STEAM-approach where the A stands for art, has raised a lot of academic interest in the past decade.
Erna Piila, Hannu Salmi, Helena Thuneberg   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

EVALUATION OF SUSTAINABILITY-ORIENTED TRANSVERSAL COMPETENCIES IN ENGINEERING POSTGRADUATE STUDIES [PDF]

, 2020
[EN] In recent times, education for sustainability is gaining more and more relevance in the field of engineering. One of the recently established Sustainable Development Goals explicitly calls for the achievement of sustainable infrastructures by 2030 ...
Antonio J. Sánchez-Garrido, Yepes, V., Victor Yepes, Navarro -Martinez, Ignacio Javier, Sánchez-Garrido, A.J., Ignacio J. Navarro   +5 more
core   +1 more source

Mobilizing transversal competencies: Insights from initial teacher training

Ricerche di Pedagogia e Didattica
The aim of this study was to understand how department heads, teacher trainers, pedagogy students, school principals, and teachers promote the development of transversal competencies such as leadership, teamwork, and conflict resolution in initial ...
Carmen Gloria Covarrubias Apablaza, Michelle Mendoza Lira, Yorka Rodríguez Ahumada, Emilia Reyes Pinto   +3 more
doaj   +1 more source