Results 71 to 80 of about 1,364,085 (279)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The Development of Soft Skills through Music in Educational Contexts: A Systematic Review

open access: yesEducation Sciences, 2023
Numerous scientific studies confirm that music is a tool to improve and develop interpersonal skills. These skills, such as leadership, teamwork, communication, interpersonal skills, or coordination.
Mario Diz-Otero   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Fostering Transversal Skills Through Open Schooling Supported by the CARE-KNOW-DO Pedagogical Model and the UNESCO AI Competencies Framework

open access: yesInternational Journal of Artificial Intelligence in Education
This study breaks new ground in educational theory by empirically validating how artificial intelligence (AI) competencies emerge through social learning ecosystems in underserved communities. Through an innovative cross-national mixed-methods design, we
Alexandra Okada   +3 more
semanticscholar   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Significance of Educational Methods in Shaping Graduates’ Competencies in Belarus

open access: yesJournal of Teaching and Learning
This paper analyses higher education graduates’ feedback on how teaching-learning methods enhance competencies. The analysis focuses on Belarus and uses data from the Fostering Competencies Development in Belarusian Higher Education (FOSTERC) survey, an
Isidora Navarro-Milla   +2 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Key Professional Competencies for Graduates in the Job Market: An Analysis of Employer Expectations in 2024

open access: yesStudies and Scientific Researches: Economics Edition
This article presents some of the results of a study on the importance that employers attach to some of the professional competencies of university graduates, as well as on the level of satisfaction with graduates' competencies, respectively the need to
Laura Timiras   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy