Results 91 to 100 of about 30,780 (260)
Gaceta Sanitaria, 2007 Se describe el diseño y los indicadores de respuesta de un estudio transversal para estimar diferentes parámetros del riesgo cardiovascular en la población de Castilla y León. Se obtuvo una muestra de 4.950 personas de 15 y más años de edad en dos etapas:
A. Tomás Vega Alonso +5 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Revista Latinoamericana de Tecnología Educativa, 2019 Este artículo se centra en el análisis de un proceso co-diseño de prácticas educativas abiertas (PEA) para el desarrollo de competencias transversales en el contexto de una universidad a distancia.
Mildred Acuña-Sossa +1 more
doaj +1 more source
OPTIMAL KINEMATIC DESIGN OF A CAR AXLE GUIDING MECHANISM IN MBS SOFTWARE ENVIRONMENT [PDF]
Fiabilitate şi Durabilitate, 2015 This work deals with the optimal kinematic design of the guiding mechanism used for the rear axle of a motor vehicle. A guiding mechanism of type 2S1C (S - sphere, C - circle) is taken into consideration, the optimization study being conducted by using
Cătălin ALEXANDRU
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Transversal Competencies in Operating Room Nurses: A Hierarchical Task Analysis
Nursing ReportsBackground: Ensuring the safety of patients in the operating room, through the monitoring and prevention of adverse events is a central priority of healthcare delivery.
Francesca Reato +8 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
No-Go Theorem on Fault Tolerant Gadgets for Multiple Logical Qubits
PRX QuantumIdentifying stabilizer codes that admit fault tolerant implementations of the full logical Clifford group would significantly advance fault tolerant quantum computation, as such implementations prevent uncontrolled error propagation.
Aranya Chakraborty, Daniel Gottesman
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source