Results 81 to 90 of about 487,112 (291)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Localized Photonic jets from flat 3D dielectric cuboids in the reflection mode
, 2015 A photonic jet (terajet at THz frequencies) commonly denotes a specific spatially localized region in the near-field at the front side of a dielectric particle with diameter comparable with wavelength illuminated with a plane wave from its backside (i.e.,
Beruete, M. +3 more
core +1 more source
Transversal Designs of Block Size Eight and Nine
European Journal of Combinatorics, 1996 The author uses a mixture of direct and recursive constructions to almost settle the existence problem for transversal designs with index \(\lambda> 1\) and block sizes \(k= 8\) and \(k= 9\) (with just a few open cases). This is a major result, since it is the first result that goes beyong the work of Hanani who settled the corresponding problem for ...
openaire +2 more sources
Education SciencesSocial changes in higher education have led to a transformation in teaching innovation for developing a critical and creative mentality in students.
Nuria Navarro +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Interference of coherent spin waves in micron-sized ferromagnetic waveguides
, 2011 We present experimental observations of the interference of spin-wave modes propagating in opposite directions in micron-sized NiFe-waveguides. To monitor the local spin-wave intensity distribution and phase of the formed interference pattern, we use ...
Bayer +21 more
core +1 more source
Performance of a variable-rate distribution system for simultaneous fertilizer application
Revista Brasileira de Engenharia Agrícola e Ambiental, 2016 The objective of this study was to evaluate the performance of a variable-rate fertilizer distribution system for coffee crop, simultaneously applying two products.
Murilo M. de Barros +5 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
MachinesIn this work, the analysis of the acoustic emission (AE) signal in grinding processes is addressed. The proposed analysis method decomposes the acoustic signal into three frequency ranges.
Piotr Sender +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source