Results 61 to 70 of about 74,349 (302)
Product Advanced Design: A Cultural Intermediation Between Knowledge and Information
DIID, 2021 Digital transformation (DX) drives transversal change, breaking disciplinary silos to transition to more sustainable paradigms through new ontological and epistemological frameworks. This has consequences on product design and development too:
Elisabetta Cianfanelli +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Applied Sciences, 2020 Background: The transversal maxillary deficiency represents one of the most frequent skeletal discrepancies of the craniofacial region. The analysis of morphological characteristics of the maxilla can be detrimental for a correct diagnosis and treatment ...
Vincenzo Quinzi +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Sensors, 2011 Fiber Bragg gratings written in highly birefringent microstructured optical fiber with a dedicated design are embedded in a composite fiber-reinforced polymer.
Hugo Thienpont +13 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Dual-Band Tunable Recursive Active Filter
, 2011 This letter presents a novel recursive active filter topology that provides dual-band performance, with independent tuning capability in both bands. The dual-band operation is achieved by using two independent feedback lines.
García Pérez, Oscar Alberto +7 more
core +1 more source
Design of a Transverse Flux Linear Motor [PDF]
Journal of Magnetics, 2011 This paper presents design procedures of a transverse flux linear motor (TFLM). The minimum and maximum flux linkage was determined by the simplified equivalent magnetic circuit and estimated average magnetic flux density at the air gap region by considering the shape of applied magnetomotive force (MMF).
Jung-Hwan Chang +2 more
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A Deterministic Approach of Merging of Blocks in Transversal Design based Key Predistribution [PDF]
, 2009 Transversal Design is a well known combinatorial design that has been used in deterministic key predistribution scheme. Merging of blocks in a design sometimes helps to obtain a key predistribution scheme with better performance.
Anupam Pattanayak, B. Majhi
core