Results 131 to 140 of about 18,049 (290)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

How teachers can use the 3T PLAY trident framework to design an activity that develops transversal skills

AVP-E ...
de Lima, Joelyn, Isaac, Siara Ruth
core   +1 more source

Performance of a core of transversal skills: self-perceptions of undergraduate medical students. [PDF]

BMC Med Educ, 2016
Ribeiro L, Severo M, Ferreira MA.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Innovative teaching pedagogies, interculturality and transversal skills

, 2019
In line with the previous three conferences (two were held at Shanghai Normal University in China in 2016 and 2017 and one at Utah Valley University in the United States in 2018), the overall objective of the 4th International Teaching Forum will be to ...

core  

Integrating Transversal Skills in Hospitality and Tourism Curricula: Practical Recommendations from Faculty.

Transversal skills have gained increased attention due to rapid technological advances. As AI solutions emerge and new jobs arise from digital access and growing work-age populations (World Economic Forum, 2025), academics must reassess teaching methods ...
Cronin, Brendan, Zwissig, Iris
core   +1 more source

The Development of Transversal Skills in Music Lessons in Primary School

, 2020
Zanes Martinsones maģistra darbs izglītības zinātnēs “Caurviju prasmju veidošanās iespējas mūzikas stundās jaunākajā skolas vecumposmā” izstrādāts Latvijas Universitātes Pedagoģijas, psiholoģijas un mākslas fakultātes Izglītības zinātņu un pedagoģisko ...
Martinsone, Zane
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Hires-PhD: a transversal skills framework for diversifying PhD employability

Humanities & Social Sciences Communications
This study aims to enhance the industrial employability of PhD graduates through the development of the HIRES-PhD framework, an abbreviation of High Impact Research and Employability Skills for the PhD. It identifies and categorizes essential transversal
Debashish Roy, María Dolores Jiménez López, María Ercilia García Álvarez   +2 more
doaj   +1 more source