Results 141 to 150 of about 18,049 (290)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Enhancing the Employability of Graduate Students with Transversal Skills [PDF]

, 2019
Unemployment has been a persistent issue in Europe for a long time despite several initiatives from policymakers. Unlike previous research, this research sees the problem from a different perspective.
Nguyen, Phuong
core  

Assessing transversal skills in the framework of an interdisciplinary program

, 2018
The paper discusses the assessment of transversal skills in the framework of a 9-month interdisciplinary programme – the China Hardware Innovation Camp (CHIC) – that runs across 3 institutions in Switzerland and includes a short-term study abroad (STSA) in China.
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Competențele transversale necesare angajaților din industria IT: relevanță și impact

Revista Transilvană de Ştiinţe Administrative
This study explores the role of transversal skills in the employability of IT professionals. While tech­nical expertise is essential, employers increasingly value critical thinking, adaptability, communication, and teamwork.
Adriana Cristian
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Are engineering teachers ready to leverage the power of play to teach transversal skills?

What conceptions do teachers hold about learning activities to develop students’ transversal skills? This qualitative exploration at a research-intensive engineering school draws on interviews and focus groups to explore teachers’ ideas about developing ...
Jalali, Yousef, Jessica Dehler, Isaac, Siara Ruth, Petringa, Natascia, Tormey, Roland   +4 more
core  

Prepared to work? The role of transversal skills in transition-to-work

, 2017
The complexity and instability that characterises the current labour market have brought new challenges to the employability of recent graduates. The study “Prepared to work” identified and analyzed the transversal and professional skills (“soft ...
Vieira, Diana Aguiar, Costa, Laura Gil, Marques, Ana Paula   +2 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source