Results 21 to 30 of about 6,068 (107)

Delirium, thrombocytopenia, insomnia, and mild liver damage associated with MAOI withdrawal [PDF]

, 2009
International ...
Bellon, Alfredo, Coverdale, John H.
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Parameters for irreversible inactivation of monoamine oxidase [PDF]

, 2020
Funding:RRR, AA, SH and SB are grateful to COST Action CA13153 for facilitating their collaboration and funding short-term visits. AA acknowledges funding under P1-0005 (Slovenian Research Agency).
Albreht, Alen, Basile, Livia, Bryant, Sharon, Guccione, Salvatore, Hagenow, Stefanie, Maniquet, Antonin, Pappalardo, Matteo, Ramsay, Rona R., Saija, Maria Chiara   +8 more
core   +1 more source

Signal transduction and modulating pathways in tryptamine-evoked vasopressor responses of the rat isolated perfused mesenteric bed [PDF]

, 2013
Tryptamine is an endogenous and dietary indoleamine-based trace amine implicated in cardiovascular pathologies, including hypertension, migraine and myocardial infarction.
Anwar, Mohammad Akhtar, Broadley, Kenneth John, Ford, William Richard, Herbert, Amy Angharad   +3 more
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Age influences the effects of nicotine and monoamine oxidase inhibition on mood-related behaviors in rats [PDF]

, 2010
Epidemiological studies have demonstrated a comorbidity of smoking with depression and anxiety, particularly during adolescence. However, few animal studies have considered possible synergistic interactions between nicotine and other tobacco smoke ...
A Lewis, A Ramos, AL Vale, AM Ouagazzal, Anne-Sophie Villégier, AS Villégier, AS Villégier, AS Villégier, Brittney Gallager, CD Morris, CD Spielberger, CJ Slawecki, D Balfour, DH Overstreet, DM Fergusson, EE Irvine, EJ Khantzian, EM Marco, Frances M. Leslie, G Engberg, G Laviola, G Vazquez-Palacios, G Vazquez-Palacios, GB Baker, HP Upadhyaya, I Lucki, J Cao, James D. Belluzzi, JB Dwyer, JC Shih, JF Cryan, JF Cryan, JF Cryan, Jon Heston, JS Fowler, JS Fowler, JS Fowler, K Lasser, KT O’Leary, L Galindo-Charles, L Prut, M Snyder, MF Poirier, N Breslau, PJ Kenny, RD Porsolt, Report USGs, RJ Salin-Pascual, S Cheeta, S Hogg, S Shiffman, S Shimazu, S Tucci, SE File, WM Daniels, X Li, Y Tizabi   +56 more
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High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit [PDF]

, 2015
Antidepressants (ADs) are used as first-line treatment for most stress-related psychiatric disorders. The alterations in brain circuit dynamics that can arise from stress exposure and underlie therapeutic actions of ADs remain, however, poorly understood.
Andrés Uribe, Florian Hladky, Florian Holsboer, Jens Stepan, Mathias V. Schmidt, Matthias Eder   +5 more
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Clinically Relevant Drug Interactions with Monoamine Oxidase Inhibitors. [PDF]

, 2022
Monoamine oxidase inhibitors (MAOI) are a class of drugs that were originally developed for the treatment of depression but have since been expanded to be used in management of affective and neurological disorders, as well as stroke and aging-related ...
Burroughs, Caroline R., Cornett, Elyse M., Edinoff, Amber N, Kaye, Adam M., Kaye, Alan David, Odisho, Amira S., Raslan, Walid A., Stark, Cain W., Swinford, Connor R.   +8 more
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Metabolism of 6:2 Fluorotelomer Alcohol by CYP 2A6 [PDF]

, 2021
Oxidation is one of the major mechanisms leading to the bioactivation of toxicants [1]. Identification of the CYPs driving the oxidation could be used to identify the possibility of localized toxicity. This project identifies CYP 2A6 as a possible enzyme
Daramola, Oluwadamilola
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Evaluation of responses to 5-HT-enhancing drugs in NMRI mice [PDF]

, 2015
In humans, the ingestion of the combination of two or more serotonin (5-HT)-enhancing drugs but also of a single drug in overdose can induce serious adverse effects, which are characteristics of the serotonin syndrome (SS).
Bert, Bettina, Fink, Heidrun, Haberzettl, Robert   +2 more
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Multitarget Drugs: an Epigenetic Epiphany [PDF]

, 2016
Epigenetics refers to changes in a biological phenotype that are not due to an underlying change in genotype. In eukaryotes, epigenetics involves a set of chemical modifications of the DNA and the histone proteins in nucleosomes.
Atkinson, Baell, Baud, Beckers, Bentley, Blagodatski, Borretto, Bowman, Brand, Burg, Cai, Chen, Chen, Chen, Chen, Ciceri, Dancy, Deans, Fahy, Filippakopoulos, Finley, Fischer, Fuhrmann, Galloway, Gjertsen, Griffith, Guerrant, Guerrant, Hantschel, He, Huang, Hui, Hurley, Jing, Kaniskan, Kingston, Ko, Kortüm, Kozikowski, Lamblin, Lan, Ling, Liu, Lu, Lu, Maes, Mahboobi, Mahboobi, Mai, McGinty, McPherson, Micelli, Moore, Mottamal, Pachaiyappan, Pastor, Patel, Pereira, Pińa, Qian, Rask-Andersen, Rose, Rothbart, Rotili, Saijo, Saijo, Samatar, Schapira, Suganuma, Tavera-Mendoza, Villalba, Wagner, Winter, Wright, Yu, Yuan, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zheng, Zuo, Álvarez   +84 more
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Safety and Efficacy of Adjunctive Esketamine vs. MAOIs in TRD in Adults [PDF]

, 2023
Background: Depression affects millions globally - Treatment-resistant depression (TRD) is defined as failure to respond to two antidepressant trials of adequate dose and duration Traditional Treatment for TRD: Switching or adding medications atypical ...
Guinan, Riley
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