Results 31 to 40 of about 4,431,538 (308)

How to change the oligomeric state of a circular protein assembly: switch from 11-subunit to 12-subunit TRAP suggests a general mechanism [PDF]

, 2011
Many critical cellular functions are performed by multisubunit circular protein oligomers whose internal geometry has evolved to meet functional requirements.
Antson, Alfred A, Antson, A., Merlino, N., Natalie Merlino, Chen, Chao-Sheng, Guy G. Dodson, Merlino, Natalie, Alfred A Antson, Dodson, Guy G, Shevtsov, Mikhail B, Dodson, G., Paul Gollnick, Gollnick, Paul, Alfred A. Antson, Shevtsov, Misha, Chao-Sheng Chen, Smits, Callum, Mikhail B Shevtsov, Smits, C., Callum Smits, Mikhail B. Shevtsov, Guy G Dodson, Gollnick, P., Chen, C.   +23 more
core   +2 more sources

AoSsk1, a Response Regulator Required for Mycelial Growth and Development, Stress Responses, Trap Formation, and the Secondary Metabolism in Arthrobotrys oligospora

Journal of Fungi, 2022
Ssk1, a response regulator of the two-component signaling system, plays an important role in the cellular response to hyperosmotic stress in fungi.
Ke-Xin Jiang, Qian-Qian Liu, Na Bai, Mei-Chen Zhu, Ke-Qin Zhang, Jin-Kui Yang   +5 more
doaj   +1 more source

Aolatg1 and Aolatg13 Regulate Autophagy and Play Different Roles in Conidiation, Trap Formation, and Pathogenicity in the Nematode-Trapping Fungus Arthrobotrys oligospora

Frontiers in Cellular and Infection Microbiology, 2022
Autophagy is a conserved cellular recycling and trafficking pathway in eukaryotes that plays an important role in cell growth, development, and pathogenicity. Atg1 and Atg13 form the Atg1–Atg13 complex, which is essential for autophagy in yeast. Here, we
Duanxu Zhou, Duanxu Zhou, Yingmei Zhu, Yingmei Zhu, Na Bai, Na Bai, Meihua Xie, Ke-Qin Zhang, Ke-Qin Zhang, Jinkui Yang, Jinkui Yang   +10 more
doaj   +1 more source

AoMae1 Regulates Hyphal Fusion, Lipid Droplet Accumulation, Conidiation, and Trap Formation in Arthrobotrys oligospora

Journal of Fungi, 2023
Malate dehydrogenase (MDH) is a key enzyme in the tricarboxylic acid (TCA) cycle and is essential for energy balance, growth, and tolerance to cold and salt stresses in plants. However, the role of MDH in filamentous fungi is still largely unknown.
Yankun Liu, Meichen Zhu, Wenjie Wang, Xuemei Li, Na Bai, Meihua Xie, Jinkui Yang   +6 more
doaj   +1 more source

Extended follow-up following a phase 2b randomized trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya [PDF]

, 2007
Background. "FFM ME-TRAP'' is sequential immunisation with two attenuated poxvirus vectors (FP9 and modified vaccinia virus Ankara) delivering the pre-erythrocytic malaria antigen ME-TRAP.
Gilbert, SC, Lang, Trudie, Bejon, P, Hill, Adrian, Tabitha Mwangi, Kevin Marsh, Hill, AVS, Gilbert Sarah C., Gilbert, Sarah, Lang Trudie, Lang, T, Peshu, N, Mwangi Tabitha, Edna Ogada, Norbert Peshu, Hill, Adrian VS, Paul Milligan, Greg Fegan, Fegan Greg, Milligan Paul, Gilbert, Sarah C, Peshu, Norbert, Philip Bejon, Bejon, Philip, Milligan, Paul, Marsh Kevin, Marsh, K, Mwangi, T, Hill Adrian V.S., Fegan, G, Mwangi, Tabitha, Peshu Norbert, Trudie Lang, Bejon Philip, Ogada Edna, Fegan, Greg, Milligan, P, Ogada, Edna, Adrian V S Hill, Ogada, E, Marsh, Kevin, Sarah C Gilbert, Hill, AV   +42 more
core   +2 more sources

Functional analysis of seven regulators of G protein signaling (RGSs) in the nematode-trapping fungus Arthrobotrys oligospora

Virulence, 2021
Regulators of G protein signaling (RGSs) are proteins that negatively regulate G protein signal transduction. In this study, seven putative RGSs were characterized in the nematode-trapping (NT) fungus, Arthrobotrys oligospora.
Ni Ma, Yining Zhao, Yunchuan Wang, Le Yang, Dongni Li, Jiangliu Yang, Kexin Jiang, Ke-Qin Zhang, Jinkui Yang   +8 more
doaj   +1 more source

The Autophagy-Related Gene Aolatg4 Regulates Hyphal Growth, Sporulation, Autophagosome Formation, and Pathogenicity in Arthrobotrys oligospora

Frontiers in Microbiology, 2020
Autophagy plays an important role in cell growth and development. The autophagy-related gene atg4 encodes a cysteine protease, which can cleave the carboxyl terminus of Atg8, thus plays a role in autophagosome formation in yeast and filamentous fungi ...
Duanxu Zhou, Meihua Xie, Na Bai, Le Yang, Ke-Qin Zhang, Jinkui Yang   +5 more
doaj   +1 more source

H2 Inhibits the Formation of Neutrophil Extracellular Traps

JACC: Basic to Translational Science, 2022
Neutrophil extracellular traps (NETs) contribute to inflammatory pathogenesis in numerous conditions, including infectious and cardiovascular diseases, and have attracted attention as potential therapeutic targets. H2 acts as an antioxidant and has been clinically and experimentally proven to ameliorate inflammation.
Shirakawa, Kohsuke, Kobayashi, Eiji, Ichihara, Genki, Kitakata, Hiroki, Katsumata, Yoshinori, Sugai, Kazuhisa, Hakamata, Yoji, Sano, Motoaki   +7 more
openaire   +2 more sources

Optimization of megakaryocyte trapping for platelet formation in microchannels

Chemical Industry and Chemical Engineering Quarterly, 2022
Platelets (PLTs) are responsible for stopping bleeding. They are small cell fragments produced from megakaryocytes (MKs) in the bone marrow. Low platelet count is a significant health problem for a patient. PLTs can usually be stored for up to 5 days prior to transfusion.
Baydar Atak, Gunay, Oruc, Muhammed Enes, Insel, Mert Akın, Sadıkoğlu, Hasan   +3 more
openaire   +4 more sources

Equilibrium Thermodynamics, Formation, and Dissociation Kinetics of Trivalent Iron and Gallium Complexes of Triazacyclononane-Triphosphinate (TRAP) Chelators: Unraveling the Foundations of Highly Selective Ga-68 Labeling

Frontiers in Chemistry, 2018
In order to rationalize the influence of FeIII contamination on labeling with the 68Ga eluted from 68Ge/68Ga-generator, a detailed investigation was carried out on the equilibrium properties, formation and dissociation kinetics of GaIII- and FeIII ...
Adrienn Vágner, Attila Forgács, Ernő Brücher, Imre Tóth, Alessandro Maiocchi, Alexander Wurzer, Hans-Jürgen Wester, Johannes Notni, Zsolt Baranyai, Zsolt Baranyai   +9 more
doaj   +1 more source