Results 41 to 50 of about 4,431,538 (308)
Nuclear Fusion, 2023 Compliance with imposed hydrogen concentration limits in the lithium loop of the DEMO-Oriented Neutron Source (DONES) requires the installation of an yttrium-based hydrogen trap.
S.J. Hendricks +3 more
doaj +1 more source
Metabolic requirements for neutrophil extracellular traps formation [PDF]
Immunology, 2015 SummaryAs part of the innate immune response, neutrophils are at the forefront of defence against infection, resolution of inflammation and wound healing. They are the most abundant leucocytes in the peripheral blood, have a short lifespan and an estimated turnover of 1010 to 1011 cells per day.
Oscar, Rodríguez-Espinosa +4 more
openaire +2 more sources
Polyphosphate-mediated inhibition of tartrate-resistant acid phosphatase and suppression of bone resorption of osteoclasts. [PDF]
PLoS ONE, 2013 Inorganic polyphosphate (poly(P)) has recently been found to play an important role in bone formation. In this study, we found that tartrate-resistant acid phosphatase (TRAP), which is abundantly expressed in osteoclasts, has polyphosphatase activity ...
Kana Harada +7 more
doaj +1 more source
Mast Cell Tryptase Potentiates Neutrophil Extracellular Trap Formation
Journal of Innate Immunity, 2021 Previous research has indicated an intimate functional communication between mast cells (MCs) and neutrophils during inflammatory conditions, but the nature of such communication is not fully understood.
Gunnar Pejler +6 more
doaj +1 more source
Formation of bright solitary matter-waves [PDF]
, 2012 This thesis presents the development of an experimental apparatus to produce Bose-Einstein condensates (BECs) with tunable interparticle interactions.
MARCHANT, ANNA,LOUISE
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Calcium ionophore-activated platelets induce eosinophil extracellular trap formation
Allergology International, 2023 Background: Platelets play a modulatory role in inflammatory response by secreting a vast array of granules and disintegrating into membrane-bound microparticles upon activation.
Myeong Seong Sim +8 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Journal of FungiThe nematode-trapping fungus (NTF) Arthrobotrys oligospora (A. oligospora) is a promising biocontrol agent, but the transcriptional regulators governing its predation remain poorly understood.
Ruobing Li +11 more
doaj +1 more source