Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. [PDF]
, 2017 The importance of extracellular traps (ETs) in innate immunity is well established, but the molecular mechanisms responsible for their formation remain unclear and in scientific dispute.
Simon, Hans-Uwe +9 more
core +1 more source
H2 Inhibits the Formation of Neutrophil Extracellular Traps
JACC: Basic to Translational Science, 2022 Neutrophil extracellular traps (NETs) contribute to inflammatory pathogenesis in numerous conditions, including infectious and cardiovascular diseases, and have attracted attention as potential therapeutic targets. H2 acts as an antioxidant and has been clinically and experimentally proven to ameliorate inflammation.
Shirakawa, Kohsuke +7 more
openaire +2 more sources
Optimization of megakaryocyte trapping for platelet formation in microchannels
Chemical Industry and Chemical Engineering Quarterly, 2022 Platelets (PLTs) are responsible for stopping bleeding. They are small cell fragments produced from megakaryocytes (MKs) in the bone marrow. Low platelet count is a significant health problem for a patient. PLTs can usually be stored for up to 5 days prior to transfusion.
Baydar Atak, Gunay +3 more
openaire +4 more sources
Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. [PDF]
, 2018 The asthmatic airways are highly susceptible to inflammatory injury by air pollutants such as ozone (O ), characterized by enhanced activation of eosinophilic granulocytes and a failure of immune protective mechanisms. Eosinophil activation during asthma
Aeschlimann, Salome +27 more
core +1 more source
Polyphosphate-mediated inhibition of tartrate-resistant acid phosphatase and suppression of bone resorption of osteoclasts. [PDF]
PLoS ONE, 2013 Inorganic polyphosphate (poly(P)) has recently been found to play an important role in bone formation. In this study, we found that tartrate-resistant acid phosphatase (TRAP), which is abundantly expressed in osteoclasts, has polyphosphatase activity ...
Kana Harada +7 more
doaj +1 more source
Mast Cell Tryptase Potentiates Neutrophil Extracellular Trap Formation
Journal of Innate Immunity, 2021 Previous research has indicated an intimate functional communication between mast cells (MCs) and neutrophils during inflammatory conditions, but the nature of such communication is not fully understood.
Gunnar Pejler +6 more
doaj +1 more source
Metabolic requirements for neutrophil extracellular traps formation [PDF]
Immunology, 2015 SummaryAs part of the innate immune response, neutrophils are at the forefront of defence against infection, resolution of inflammation and wound healing. They are the most abundant leucocytes in the peripheral blood, have a short lifespan and an estimated turnover of 1010 to 1011 cells per day.
Oscar, Rodríguez-Espinosa +4 more
openaire +2 more sources
Calcium ionophore-activated platelets induce eosinophil extracellular trap formation
Allergology International, 2023 Background: Platelets play a modulatory role in inflammatory response by secreting a vast array of granules and disintegrating into membrane-bound microparticles upon activation.
Myeong Seong Sim +8 more
doaj +1 more source
Formation of bright solitary matter-waves [PDF]
, 2012 This thesis presents the development of an experimental apparatus to produce Bose-Einstein condensates (BECs) with tunable interparticle interactions.
MARCHANT, ANNA,LOUISE
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source