Results 71 to 80 of about 4,431,538 (308)

Formation fluid characteristics and hydrocarbon accumulation in the Dongying sag, Shengli Oilfield

open access: yesPetroleum Exploration and Development, 2012
Based on the analysis of geochemical characteristics and distribution of different formation waters, a new origin identification standard was established for the formation water in the Paleogene Shahejie Formation in the Dongying Sag. The migration paths
Shanwen ZHANG   +8 more
doaj   +1 more source

Rac2 is required for the formation of neutrophil extracellular traps [PDF]

open access: yesJournal of Leukocyte Biology, 2011
ABSTRACTNeutrophils play a critical role as a first line of defense against invading pathogens. Recently, a new defense strategy of neutrophils was described, in which pathogens are trapped and killed by NETs. However, the exact underlying mechanisms leading to the formation of NETs remain elusive. Here, we explored the role of the Rac small GTPases in
Lim, MB   +4 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Carbon dioxide baited trap catches do not correlate with human landing collections of Anopheles aquasalis in Suriname [PDF]

open access: yes, 2011
Three types of carbon dioxide-baited traps, i.e., the Centers for Disease Control Miniature Light Trap without light, the BioGents (BG) Sentinel Mosquito Trap (BG-Sentinel) and the Mosquito Magnet® Liberty Plus were compared with human landing ...
Koenraadt, Constantianus Johanna Maria   +15 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Histone Acetylation Promotes Neutrophil Extracellular Trap Formation

open access: yesBiomolecules, 2019
Neutrophils undergo a unique form of cell death to generate neutrophil extracellular traps (NETs). It is well established that citrullination of histones (e.g., CitH3) facilitates chromatin decondensation during NET formation (NETosis), particularly ...
Hussein J. Hamam   +2 more
doaj   +1 more source

On the mechanism of trapped surface formation

open access: yes, 1993
By a combination of analytical and numerical methods, the density profile of a momentarily at rest spherical star is varied, and the corresponding response in the area of the spherical shells is monitored. It is shown that the inner apparent horizon (if it exists) must lie within or at most on the star's surface, while no such restriction is found for ...
Valls-Gabaud, David, Zannias, Thomas
openaire   +2 more sources

Inflation Targeting and the Liquidity Trap [PDF]

open access: yes
This paper considers whether "liquidity trap" issues have important bearing on the desirability of inflation targeting as a strategy for monetary policy.
Bennett T. McCallum
core  

Electronic spectroscopy of cold cations in a 22-pole trap by indirect methods [PDF]

open access: yes, 2013
The confining capabilities of a 22-pole ion trap have been employed to mea- sure electronic spectra of cations of astrophysical relevance. The ion trap sits on the head of a closed cycle cryostat, enabling collisional cooling of the confined ions with
Chakrabarty, Satrajit
core   +1 more source

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