Results 71 to 80 of about 204,702 (299)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
A Quantum Degenerate Mixture of $^{87}$Rb and $^{133}$Cs [PDF]
, 2011 This thesis reports the formation of a dual-species Bose-Einstein condensate of $^{87}$Rb and $^{133}$Cs in the same trapping potential. Quantum degenerate mixtures exhibit rich physics inaccessible to single species experiments and provide an ideal ...
MCCARRON, DANIEL,JOHN
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Realisation of a cold mixture of rubidium and caesium [PDF]
, 2008 This thesis describes a new apparatus designed to study cold, ultracold, and quantum degenerate mixtures of rubidium and caesium atoms. The Rb- Cs mixture is prepared using a double magneto-optical trap (MOT) system in which a two-species pyramid MOT ...
Harris, Magaret L, Harris, Margaret L.
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Frontiers in Immunology, 2016 In this study we identified and characterized the potential of a high ratio of bicarbonate to CO2 and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation.
Christian Maueröder +14 more
doaj +1 more source
Desenvolvimento de método para a determinação de trihalometanos em águas de Florianópolis - SC usando Purge & Trap e cromatografia gasosa [PDF]
, 2005 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.Neste trabalho foi determinada à quantidade de trihalometanos (THM) em diversos tipos de água da região de ...
Budziak, Dilma
core
Dynamic Trap Formation and Elimination in Colloidal Quantum Dots
, 2015 Using first-principles simulations on PbS and CdSe colloidal quantum dots, we find that surface defects form in response to electronic doping and charging of the nanoparticles.
S. M. Thon (1294191) +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Trapping parameters comparison between cable sections from different service conditions by a new trapping-detrapping model [PDF]
, 2014 Space charge formation will cause electric field enhancement at certain location in the polymeric materials, especially under HVDC insulation condition.
Xu, Yang +5 more
core +1 more source