Results 121 to 130 of about 99,908 (306)

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

A Pollen‐Enhanced Bionic Mechanoreceptor Induced by Asymmetric Ionic Convection in Hydrogel for Sensory‐Augmented Prostheses

Advanced Science, EarlyView.
This work proposed a pollen‐enhanced bionic mechanoreceptor based on ionic convection. Leveraging the ion anchoring effect of the pollen particle, the output performance could be ∼12 times higher than the original state. By employing deep learning models as AI brains, the feasibility of a sensory‐augmented prosthesis consisting of a pollen‐enhanced ...
Zi Hao Guo, Jingyu Deng, Yanzhang Xu, Chenchen Zhou, Yangshi Shao, Xiong Pu, Munho Kim, Namjoon Cho   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Traumatic Brain Injury 2014 Other title: TBI 2014

, 2016
"Released November 2016.""Traumatic brain injury (TBI) is a serious public health problem in Kansas and in the United States. A TBI is caused by a bump, blow, jolt, or penetration to the head that disrupts the normal function of the brain.
Special Emphasis Report: Traumatic Brain Injury 2014
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

The Impact of Early Childhood Traumatic Brain Injury on the Transition to School

, 2014
Traumatic brain injury (TBI) is a common cause of pervasive and long lasting disability and injury. The outcomes of TBI in young children can be particularly detrimental, due to the impact on both current functioning and the ability to acquire new skills.
Hannah, Jessica Shirley
core  

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

ROLE OF TRANSOCULAR ULTRASOUND IN IDENTIFYING RAISED INTRACRANIAL PRESSURE AND PREDICTING INTRACRANIAL BLEED IN TRAUMATIC BRAIN INJURIES

Pakistan Armed Forces Medical Journal, 2019
Objective: To know the efficacy of transocular ultrasound (TOU) in identification of elevated intracranial pressure (eICP) and early prediction of intracranial bleed in traumatic brain injuries (TBI). Study Design: Descriptive study.
Muhammad Asim Ghauri, Ahmed Mujadid Khan Burqi, Anum Sultan, Hassan Masood, Hassan Masood, Muhammad Umer Hayyat, Muhammad Awais Qarni   +6 more
doaj  

Performances in the workplace following traumatic brain injury: a dramaturgical metaphor to explain how return to work is supported

, 2013
Recovery from Traumatic Brain Injury (TBI) is a lengthy and complex journey. The ability to Return to Work (RTW) is often severely compromised and not easily predicted by medical sequelae. Recent qualitative research has highlighted the importance of the
Truman, J.
core  

The pattern of traumatic brain injuries: A country undergoing rapid development

, 2010
Background: Traumatic brain injuries (TBIs) remain an important public health problem in most industrial developed and especially in developing countries.
AHMAD, Amal E., Bener, Abdulbari, AL-MULLA, Fatma H., RAHMAN, Yassir S. Abdul, OMAR, Azhar O. Kh.   +4 more
core   +1 more source