Results 61 to 70 of about 213,104 (305)

Biomarkers for traumatic brain injury [PDF]

Journal of Neurology, 2018
Traumatic brain injury (TBI) poses a major public health problem. It is amongst the leading causes of mortality in young people in developed countries, and many survivors of TBI suffer from persistent disabilities. As a result, there remains an unmet clinical need for the development of more robust diagnostic and prognostic indicators of TBI.
Ronak Ved, Malik Zaben
openaire   +4 more sources

Understanding Contributors of Resilience in Youth With Childhood‐Onset Systemic Lupus Erythematosus Through a Socioecological Lens: A Mixed‐Methods Study

Arthritis Care &Research, EarlyView.
Objective This study aimed to identify themes contributing to resilience in childhood‐onset systemic lupus erythematosus (cSLE), distinguish between profiles of resilience, and examine how they relate to underlying themes and patient characteristics. Methods We conducted a mixed‐methods study of 21 patients with cSLE aged 11 to 19 years at a Canadian ...
Isabella Zaffino, Louise Boulard, Joanna Law, Asha Jeyanathan, Lawrence Ng, Sandra Williams‐Reid, Kiah Reid, Angela Cortes, Eugene Cortes, Ashley Danguecan, Deborah M. Levy, Linda T. Hiraki, Andrea M. Knight   +12 more
wiley   +1 more source

Designing research on concussion treatment in the military setting: Important challenges to consider

Preventive Medicine Reports, 2021
Traumatic brain injury (TBI) is highly prevalent on a global scale with concussion being the most common of all TBIs. Concussion research on rehabilitation and symptom resolution is well-established, particularly among athletes, but less is known about ...
Rosemay A. Remigio-Baker, Seth Kiser, Hamid Ferdosi, Keith Stuessi, Stephanie Maxfield-Panker, Sidney R. Hinds II   +5 more
doaj  

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Sensitivity and specificity of an eye movement tracking-based biomarker for concussion

Concussion, 2016
Object: The purpose of the current study is to determine the sensitivity and specificity of an eye tracking method as a classifier for identifying concussion. Methods: Brain injured and control subjects prospectively underwent both eye tracking and Sport
Uzma Samadani, Meng Li, Meng Qian, Eugene Laska, Robert Ritlop, Radek Kolecki, Marleen Reyes, Lindsey Altomare, Je Yeong Sone, Aylin Adem, Paul Huang, Douglas Kondziolka, Stephen Wall, Spiros Frangos, Charles Marmar   +14 more
doaj   +1 more source

Polymer‐Incorporated Mechanically Compliant Carbon Nanotube Microelectrode Arrays for Multichannel Neural Signal Recording

Advanced Functional Materials, EarlyView.
This work presents a soft microelectrode array based on vertically aligned carbon nanotube (CNT) forests, combining high conductivity with mechanical softness. A densification process and air‐pressure‐assisted flexibilization improve structural integrity, ensuring stable insertion and reduced inflammation.
Hyeonhee Roh, Kwangjun Kim, Chaesung Kim, Minju Kim, Minwook Kim, Sangjun Sim, Jongbaeg Kim, Jong G. Ok, Maesoon Im   +8 more
wiley   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Feasibility and usability of microinteraction ecological momentary assessment using a smartwatch in military personnel with a history of traumatic brain injury

Frontiers in Neurology
IntroductionMicrointeraction Ecological Momentary Assessment (miEMA) addresses the challenges of traditional self-report questionnaires by collecting data in real time.
Katrina Monti, Katrina Monti, Katrina Monti, Katie Williams, Katie Williams, Katie Williams, Brian Ivins, Brian Ivins, Jay Uomoto, Jami Skarda-Craft, Michael Dretsch, Michael Dretsch, Michael Dretsch   +12 more
doaj   +1 more source