Results 61 to 70 of about 394,872 (191)

Hypoxia-inducible factor-1 alpha is involved in RIP-induced necroptosis caused by in vitro and in vivo ischemic brain injury

open access: yesScientific Reports, 2017
Necroptosis, a novel type of programmed cell death, is involved in stroke-induced ischemic brain injury. Although studies have sought to explore the mechanisms of necroptosis, its signaling pathway has not yet to be completely elucidated.
Xiao-Sa Yang   +8 more
doaj   +1 more source

New Mechanics of Traumatic Brain Injury [PDF]

open access: yesarXiv, 2008
The prediction and prevention of traumatic brain injury is a very important aspect of preventive medical science. This paper proposes a new coupled loading-rate hypothesis for the traumatic brain injury (TBI), which states that the main cause of the TBI is an external Euclidean jolt, or SE(3)-jolt, an impulsive loading that strikes the head in several ...
arxiv  

Neural Correlates of Outcome Anticipation in Multiple Sclerosis

open access: yesFrontiers in Neurology, 2018
Outcome anticipation is not only a mental preparation for upcoming consequences, but also an essential component of learning and decision-making. Thus, anticipation of consequences is a key process in everyday functioning.
Angela Spirou   +7 more
doaj   +1 more source

Epidemiology of traumatic brain injury in Europe

open access: yesActa Neurochirurgica, 2015
BackgroundTraumatic brain injury (TBI) is a critical public health and socio-economic problem throughout the world, making epidemiological monitoring of incidence, prevalence and outcome of TBI necessary.
W. Peeters   +6 more
semanticscholar   +1 more source

Unsupervised learning with GLRM feature selection reveals novel traumatic brain injury phenotypes [PDF]

open access: yesarXiv, 2018
Baseline injury categorization is important to traumatic brain injury (TBI) research and treatment. Current categorization is dominated by symptom-based scores that insufficiently capture injury heterogeneity. In this work, we apply unsupervised clustering to identify novel TBI phenotypes. Our approach uses a generalized low-rank model (GLRM) model for
arxiv  

Designing research on concussion treatment in the military setting: Important challenges to consider

open access: yesPreventive Medicine Reports, 2021
Traumatic brain injury (TBI) is highly prevalent on a global scale with concussion being the most common of all TBIs. Concussion research on rehabilitation and symptom resolution is well-established, particularly among athletes, but less is known about ...
Rosemay A. Remigio-Baker   +5 more
doaj  

A simple rat model of mild traumatic brain injury: a device to reproduce anatomical and neurological changes of mild traumatic brain injury [PDF]

open access: yesPeerJ, 2017
Mild traumatic brain injury typically involves temporary impairment of neurological function. Previous studies used water pressure or rotational injury for designing the device to make a rat a mild traumatic brain injury model.
Ho Jeong Kim, Soo Jeong Han
doaj   +2 more sources

Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injury

open access: yesJournal of Neuroinflammation, 2019
The interaction between astrocytes and microglia plays a vital role in the damage and repair of brain lesions due to traumatic brain injury (TBI). Recent studies have shown that exosomes act as potent mediators involved in intercellular communication. In
xiaobing long   +7 more
semanticscholar   +1 more source

Inflammation and neuroprotection in traumatic brain injury.

open access: yesJAMA Neurology, 2015
IMPORTANCE Traumatic brain injury (TBI) is a significant public health concern that affects individuals in all demographics. With increasing interest in the medical and public communities, understanding the inflammatory mechanisms that drive the ...
Kara N. Corps   +2 more
semanticscholar   +1 more source

New Universal Theory of Injury Prediction and Prevention [PDF]

open access: yesarXiv, 2009
The prediction and prevention of traumatic brain injury, spinal injury and general musculo-skeletal injury is a very important aspect of preventive medical science. Recently, in a series of papers, I have proposed a new coupled loading-rate hypothesis as a unique cause of all above injuries.
arxiv  

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