Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Women on the Move: How Socio-Economic Background Through Lifestyle Shapes Travel Behavior to Bali
Jurnal Aplikasi ManajemenTourism is a crucial sector for economic growth, and understanding the factors that influence travel behavior is essential for developing effective strategies.
Ni Made Dyah Ryana Kurniasari +1 more
doaj +1 more source
Impact of Subjective and Objective Factors on Subway Travel Behavior: Spatial Differentiation. [PDF]
Int J Environ Res Public Health, 2022 Chen Q, Yan Y, Zhang X, Chen J.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
ComplexityA metropolitan area is a new form of urban development under the agglomeration effect and scale economy. The renewal and upgrading of urban spatial structures have brought new pressure to urban commuting.
Dai Xin, Tianshan Ma
doaj +1 more source
Multi-modal Travel Simulation and Travel Behavior Analysis: Case Study in Shanghai
Journal of Highway and Transportation Research and DevelopmentThis study aims to investigate the multi-modal travel behavior and obtain quantitative results for various indicators by building an eqasim/MATSim model, using Shanghai as the study area.
Yue Hu, Chao Yang, Kay W Axhausen
doaj +1 more source
Explaining US travel behavior with perceived threat of pandemic, consumer sentiment, and economic policy uncertainty. [PDF]
Transp Policy (Oxf), 2023 Chi J.
europepmc +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
How mentally healthy we are during the pandemic? Findings from changed travel behavior. [PDF]
J Transp Health, 2023 Yang X, Chen P, Zhang Y.
europepmc +1 more source
Moving from Walkability? Evaluation Traditional and Merging Data Sources for Evaluating Changes in Campus-Generated Greenhouse Gas Emissions [PDF]
, 2019 Universities are increasingly committing to reduce campus-generated greenhouse gas emissions, whether voluntarily or in response to a legal mandate. As an initial step to keeping these commitments, universities need an accounting of baseline greenhouse ...
Kawahara, Troy +4 more
core +1 more source