Results 121 to 130 of about 213,940 (301)

Multi-modal Travel Simulation and Travel Behavior Analysis: Case Study in Shanghai

open access: yesJournal of Highway and Transportation Research and Development
This study aims to investigate the multi-modal travel behavior and obtain quantitative results for various indicators by building an eqasim/MATSim model, using Shanghai as the study area.
Yue Hu, Chao Yang, Kay W Axhausen
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Case Studies on Travel Behavior Data Collection in Metropolitan Regions - Briefing Note

open access: yes, 2023
A large number of people have been gathering in and around the cities. Transport infrastructure provision and land-use regulations cause cities to expand towards their outskirts creating urban sprawl (Blair, 1995; Priemus et al., 2001) and convert rural ...
Andrea SIMONE   +4 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

PERCEIVED RISK, PRICE AND ONLINE TRAVEL AGENCIES: DOES PRICE ALWAYS MATTER? [PDF]

open access: yes
The present study analyzes the influence of price level in the case of online shopping for travel services. The methodology used is a quasi experiment developed in the online environment.
Patricea Elena BERTEA   +1 more
core  

Impact of COVID-19 on adolescent travel behavior. [PDF]

open access: yesJ Transp Health, 2022
Liu J, Cao Q, Pei M.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Illusion of Motion: Variation of Subjective Value of Travel Time on Freeways and Ramp Meters [PDF]

open access: yes
This paper explores drivers' subjective value of time under moving and stopped freeway travel conditions using a stated preference survey. Unlike previous studies that assume a constant value of time, this research relates perceived satisfaction of a ...
Feng xie, Lei Zhang, David Levinson
core  

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