Results 101 to 110 of about 11,645,663 (292)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Sustainable travel behavior intervention is an essential strategy to promote the development of urban transportation. The interventions offer personalized strategies based on certain scenario and participants to promote its effectiveness over hard travel
Jian Li, Chenjie Xu
doaj +1 more source
Information, communication, travel behavior and accessibility
Over the past two decades many papers have been published on the impact of Information and Communication Technologies (ICT) on travel behavior, but the literature focusing on the impact of ICT on accessibility is relatively scarce.
Bert van Wee, Karst Geurs, Caspar Chorus
doaj +1 more source
Psychological factors are generally thought to play an important role in the prediction of individual variations in travel behavior and travel related choices.
M. Kroesen, C. Chorus
semanticscholar +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Newsletter dedicated to traveling in Texas, including information about news, locations, and events of interest to visitors as well as statistics and summaries of travel in the ...
Texas. Travel and Information Division.
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
How Do Information Interventions Influence Walking and Cycling Behavior?
In the context of promoting sustainable mobility, walking and cycling have been widely recognized for their environmental and health benefits. However, a notable gap often exists between residents’ motivation to engage in these modes and their actual ...
Wenxuan Lu +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

