Results 111 to 120 of about 213,940 (301)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Influence of The Information Search Behavior Satisfaction of Travel Blogs on Travel Intention

open access: yes, 2012
[[abstract]]Traditional tourism information focused on print ads, guide books, newspapers and magazines. The Internet provides a new, immediate, convenient, and dynamic travel information dissemination platform.
Lin, Chi-Hsyung
core  

From trajectory to behavior: Capturing individual travel details using an applet-based GPS tracking system [PDF]

open access: yes
Household travel survey data form the foundation of travel behavior modeling and transportation planning, yet traditional interview-based methods face significant challenges related to high labor costs and data quality limitations.
Yuan, Quan   +5 more
core   +1 more source

Women on the Move: How Socio-Economic Background Through Lifestyle Shapes Travel Behavior to Bali

open access: yesJurnal Aplikasi Manajemen
Tourism is a crucial sector for economic growth, and understanding the factors that influence travel behavior is essential for developing effective strategies.
Ni Made Dyah Ryana Kurniasari   +1 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Operational Evidence of Changing Travel Patterns [PDF]

open access: yes
This paper utilizes a traffic counts database covering a ten year period (1976-1985) to identify travel trends for Montgomery County, a suburb of Washington D.C. Generally, travel behavior is analyzed using person based travel survey data.
Ajay Kumar, David Levinson
core  

Commuter Travel Behavior Modeling in Metropolitan Areas Based on Cumulative Prospect Theory: A Case Study of Xi’an, China

open access: yesComplexity
A metropolitan area is a new form of urban development under the agglomeration effect and scale economy. The renewal and upgrading of urban spatial structures have brought new pressure to urban commuting.
Dai Xin, Tianshan Ma
doaj   +1 more source

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