Results 131 to 140 of about 1,163,365 (294)

Consumer innovative behavior in vacation travel [PDF]

open access: yes, 2011
This paper focuses on the study of innovative behavior of tourists through the dimensions of sensation seeking. To our knowledge, few studies have explored the dimensions of sensation seeking in relation to the innovative behavior of tourists in their ...
López-Bonilla, Jesús Manuel   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Digital Pathways to Sustainability: Eco-Travel Apps and Gen Z’s Eco-Friendly Travel Behaviors

open access: yesTourism and Hospitality
This study examines the interrelations among the perception of Gen Z towards tourism’s negative environmental impacts, adoption intentions of eco-friendly travel apps, and attitudes towards the value of these apps, as well as the mediating roles of ...
Zehra Saltik   +2 more
doaj   +1 more source

Investigating influencing factors for ICT adoption that changes travel behavior in response to the COVID-19 outbreak in Indonesia. [PDF]

open access: yesCase Stud Transp Policy, 2023
Rizki M   +5 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Analyzing the Impact of COVID-19 on Travel and Search Distances for Prominent Landmarks: Insights from Google Trends, X, and Tripadvisor

open access: yesGeographies
The COVID-19 pandemic profoundly affected people’s travel behavior and travel desires, particularly regarding trips to prominent destinations. This study explores the pandemic’s impact on travel behavior and online search patterns for 12 landmarks across
Jiping Cao   +3 more
doaj   +1 more source

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