Results 71 to 80 of about 259,075 (330)
Inter and intra-hemispheric structural imaging markers predict depression relapse after electroconvulsive therapy: a multisite study. [PDF]
, 2017 Relapse of depression following treatment is high. Biomarkers predictive of an individual's relapse risk could provide earlier opportunities for prevention.
Abbott, Christopher C +8 more
core +3 more sources
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Neuropsychopharmacology Reports, 2021 Aim Approximately one‐third of patients with major depressive disorder develop treatment‐resistant depression. One‐third of patients with treatment‐resistant depression demonstrate resistance to ketamine, which is a novel antidepressant effective for ...
Tomoyuki Nakamura +7 more
doaj +1 more source
利用三碘甲狀腺氨酸強化療法治療對於三環抗抑鬱藥物無效的濫用藥物病人 [PDF]
, 2001 We report on two substance misusers with depression resistant to tricyclic antidepressant treatment who responded to triiodothyronine augmentation.
Ho, TP, Kan, CK
core
Clinical improvements following bilateral anterior capsulotomy in treatment-resistant depression [PDF]
, 2016 The purpose of this study was to evaluate a programme of lesion surgery carried out on patients with treatment-resistant depression (TRD). This was a retrospective study looking at clinical and psychometric data from 45 patients with TRD who had ...
Bracht, Tobias +6 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
The neurobiology of treatment-resistant depression: a systematic review of neuroimaging studies.
Neuroscience and Biobehavioral Reviews, 2021 Treatment-resistant depression (TRD) is a debilitating condition associated with higher medical costs, increased illness burden, and reduced quality of life compared to non-treatment-resistant major depressive disorder (MDD).
N. Runia +6 more
semanticscholar +1 more source
Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang +7 more
wiley +1 more source
Electroconvulsive therapy mediates neuroplasticity of white matter microstructure in major depression. [PDF]
, 2014 Whether plasticity of white matter (WM) microstructure relates to therapeutic response in major depressive disorder (MDD) remains uncertain. We examined diffusion tensor imaging (DTI) correlates of WM structural connectivity in patients receiving ...
Clark, K +7 more
core +1 more source
Novel drug developmental strategies for treatment‐resistant depression
British Journal of Pharmacology, 2021 Major depressive disorder is a leading cause of disability worldwide. Because conventional therapies are ineffective in many patients, novel strategies are needed to overcome treatment‐resistant depression (TRD).
É. Borbély +5 more
semanticscholar +1 more source