Results 91 to 100 of about 75,341 (263)
ABSTRACT Background Given their modifiable nature, understanding the intrapersonal factors involved in the cessation of non‐suicidal self‐injury (NSSI) is needed to inform existing therapeutic approaches and explore novel avenues for supporting individuals with NSSI.
Caitlyn Herrick +3 more
wiley +1 more source
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad +12 more
wiley +1 more source
Efficacy and tolerability of clozapine versus quetiapine in treatment-resistant schizophrenia
Objectives: To compare the efficacy and tolerability of clozapine and quetiapine in patients with treatment-resistant schizophrenia (TRS). Patients and Methods: In this prospective, randomized, open label study of 14 weeks, 53 patients with schizophrenia
Mitesh Kumar +3 more
doaj +1 more source
Cognition in Treatment Resistant versus Non- Treatment Resistant Schizophrenia [PDF]
IntroductionDespite antipsychotic treatment, around one-third of individuals of schizophrenia remain unresponsive.ObjectivesComparing cognitive impairments in TRS versus non-TRS patients.Methods50 adult patients with schizophrenia(DSM-5) were recruited in this cross-sectional cohort study, categorised into TRS (14) (treatment-resistant schizophrenia ...
Shah S +4 more
europepmc +3 more sources
A Systematic Review of the Soteria Paradigm for the Treatment of People Diagnosed With Schizophrenia [PDF]
Background: The “Soteria paradigm” attempts to support people diagnosed with schizophrenia spectrum disorders using a minimal medication approach. Interest in this approach is growing in the United Kingdom, several European countries, North America, and ...
Calton, Tim +3 more
core +2 more sources
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma +14 more
wiley +1 more source
Risk of suicide during treatment with venlafaxine, italopram, fluoxetine, and dothiepin : retrospective cohort study [PDF]
Objective To compare the risk of suicide in adults usingthe antidepressant venlafaxine compared with citalopram, fluoxetine, and dothiepin. Design Retrospective cohort study. Setting UK General Practice Research Database. Participants 219 088 patients,
Andrews, Elizabeth +5 more
core +2 more sources
Latent Profile Analysis of Sleep Patterns in Children With Autism Spectrum Disorder
Children with autism spectrum disorder (ASD) exhibited three distinct sleep phenotypes. Cluster 3, characterized by mild sleep‐disordered breathing, showed significant improvements in core symptoms, whereas Clusters 1 and 2 demonstrated modest changes.
Ke Wang +9 more
wiley +1 more source
A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]
The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi +6 more
core +2 more sources
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve +6 more
wiley +1 more source

