Results 101 to 110 of about 26,546 (243)

Association between treatment resistance and cognitive function in schizophrenia

open access: yesSingapore Medical Journal
Introduction: Treatment-resistant schizophrenia (TRS) affects around 30% of individuals with schizophrenia. About half of the patients with TRS who are treated with clozapine do not show a meaningful clinical response, that is, clozapine resistance.
Jiaqian Sun   +6 more
doaj   +1 more source

“All that I've been through has made me who I am”: youth conceptualisations of personal recovery in mental health

open access: yesChild and Adolescent Mental Health, EarlyView.
Background Youth is a transitional period from 15 to 24 years involving developmental milestones that may be adversely affected by mental health (MH) concerns. Clinical interventions tend to focus on the reduction or cure of illness‐based psychiatric symptoms.
Linda Anderson   +12 more
wiley   +1 more source

The Politics of Preferences for Public Mental Health Insurance in Quebec

open access: yesCanadian Public Administration, EarlyView.
Abstract We study public demand for the extension of public health insurance to psychological services. Previous research neglects the interplay of self‐interest and ideology to explain individuals’ willingness to pay for public mental health care. Relying on an original survey of the Quebec population, we show that support for the extension of mental ...
Olivier Jacques, Gabriel Gosselin
wiley   +1 more source

Mothering Through the Experiences of Homelessness With a Particular Focus on Child Separation in High‐Income Countries: A Scoping Review

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Mothers who experience homelessness represent one of the most vulnerable and marginalized groups, often facing separation from their children as a consequence of housing instability and intersecting challenges. While there is a substantial body of research on parenting in the context of homelessness, little is known about the experience of ...
Olayinka Ariba   +5 more
wiley   +1 more source

Use of third-generation antipsychotics in combination with clozapine in the treatment of resistant schizophrenia

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева
The aim of the study was to analyze the pathogenesis and treatment strategies of treatment-resistant schizophrenia by searching, selecting and reviewing publications covering this topic. 42 articles were analyzed during the work, which contributed to the
A. R. Asadullin   +2 more
doaj   +1 more source

Defining and characterising treatment-resistant schizophrenia

open access: yesEuropean Psychiatry, 1995
SummaryThis paper argues for a broader definition of treatment refractoriness that would include patients with partial drug responses, a relatively recent onset, less dramatic symptoms and intolerance to conventional drugs. The drug trials that define their responsiveness should be carefully conducted over a prolonged period of time, but need not ...
openaire   +2 more sources

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

open access: yesCell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao   +6 more
wiley   +1 more source

Psychotic symptoms of sexual nature as core psychopathology in schizophrenia: Case series

open access: yesIndian Journal of Psychiatry
Background: Psychotic symptoms involving sexual content remain underreported in schizophrenia, particularly in Indian settings. Cases: Six patients with schizophrenia presenting with sexually themed delusions or hallucinations as core psychopathology ...
Anjali Sharma   +3 more
doaj   +1 more source

Holistic approach to substance‐induced psychosis

open access: yes
Addiction, EarlyView.
Julia M. Lappin   +2 more
wiley   +1 more source

Synaptic ultrastructural alterations in human focal cortical dysplasia: Insights from volume electron microscopy

open access: yesEpilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim   +6 more
wiley   +1 more source

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