Results 121 to 130 of about 59,572 (271)

Holistic approach to substance‐induced psychosis

Addiction, EarlyView.
Julia M. Lappin, Shane Darke, Michael Farrell   +2 more
wiley   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Double-blind comparison of olanzapine versus clozapine in schizophrenic patients clinically eligible for treatment with clozapine.

, 2001
The treatment of schizophrenic patients who fail to respond to adequate trials of neuroleptic drugs is a major challenge. Clozapine has been one treatment option; however, it is not universally effective and is limited in its use by safety concerns. With
Birkett, M.A., Kiesler, G.M., Wood, A.J., Tollefson, G.D.   +3 more
core   +1 more source

An Alien Word? Cosmic Salvation within a Rahnerian Framework

The Heythrop Journal, EarlyView.
Abstract The possibility of life beyond our planet raises serious theological questions for Christians, particularly in the realm of soteriology. How would Jesus of Nazareth relate to such creatures? Is he the ‘universal’ saviour, in the cosmic sense? Or are there other incarnations of the Logos, the Word or Son of God?
Brandon R. Peterson
wiley   +1 more source

Estrogens and gonadal function in schizophrenia and related psychoses [PDF]

, 2011
Recent research has increasingly pointed to the importance of estrogens and the hypothalamic-pituitary-gonadal axis in schizophrenia. Specifically, there is mounting evidence from clinical, epidemiological, and basic research that estradiol, the main ...
Riecher-Rössler, Anita, Kulkarni, Jayashri   +1 more
core  

Sensorimotor gating and clinical outcome following cognitive behaviour therapy for psychosis

, 2012
Background: Prepulse inhibition (PPI) of the startle response refers to the ability of a weak prestimulus to transiently inhibit the response to a closely following strong sensory stimulus.
Peters, Emmanuelle R., Emmanuelle R. Peters, Peters, Emmanuelle R.; id_orcid, Antonova, Elena, Preethi Premkumar, Kuipers, Elizabeth; id_orcid, Satya Raghuvanshi, Aasen, I, Kumari, V, Antonova, E, Ingrid Aasen, Kuipers, Elizabeth, Elizabeth Kuipers, Elena Antonova, Aasen, Ingrid, Premkumar, P, Anilkumar, AP, Kuipers, E, Anilkumar, Anantha P., Peters, ER, Veena Kumari, Fannon, D, Raghuvanshi, Satya, Kumari, Veena, Anantha P. Anilkumar, Dominic Fannon, Raghuvanshi, S, Fannon, Dominic, Premkumar, Preethi   +28 more
core   +1 more source

Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs, Eslam A. Elghonaimy, Praveen Ramakrishnan Geethakumari, Kiran A. Kumar, Joseph F. Merola, Heather W. Goff, Todd A. Aguilera   +6 more
wiley   +1 more source

Darier disease—A review highlighting new insights from the Darier Disease International Task Force

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz, Alain Hovnanian, Grace Xiong, Dedee Frances Murrell, Simon M. Mueller, Khaled Ezzedine, Nessa Aghazadeh Mohandesi, Ahmed Salem Aldhaheri, Nissim Asayag, Eulalia Baselga, Chen Nadler, Keith Choate, Chia‐Yu Chu, John Robert Edminister, Emmanuella Guenova, Melis Gönülal, Antoni Gostynski, Ankan Gupta, Lalit Kumar Gupta, Juliette Mazereeuw‐Hautier, Wolfram Hoetzenecker, Peter Itin, Marek Jankowski, Akiharu Kubo, Haur Yueh Lee, Julia Scott Lehman, Anfisa Lepekhova, Márta Medvecz, Jemima E. Mellerio, Verena Moosbrugger‐Martinz, Amy S. Paller, Dóra Plázár, Amadeu José Rodrigues Queiróz, Josep Riera‐Monroig, Ralph Rosa, Matthias Schmuth, Maella Severino Freire, Itzhak Shabat, Jonathan Shapiro, Cory L. Simpson, Diego Soto‐García, Alexander J. Stratigos, Gianluca Abel Tadini, Takuya Takeichi, Kaushal K. Verma, Jakob D. Wikström, Alexander Zink, Michael Ziv, Alexander Navarini, Roni Pircha Dodiuk‐Gad   +49 more
wiley   +1 more source

Conversational Artificial Intelligence in Everyday Family Life: Conceptualizing Family‐AI Interactions From a Systemic Perspective

Journal of Family Theory &Review, EarlyView.
ABSTRACT Although conversational artificial intelligence (CAI) has become increasingly integrated into daily life, research examining its role is limited to user engagement and Human‐AI interaction. The aim of this article is to review existing research on CAI use in everyday family life and conceptualize its role from a family systemic perspective ...
Gizem Erdem, Minel Guler, Melike Coskun, Gokcenay Baser   +3 more
wiley   +1 more source

Successful utilization of clozapine for a patient with treatment‐resistant schizophrenia after recurrent violent behavior

Neuropsychopharmacology Reports
Background In patients with schizophrenia, violent behavior is a clinically important factor that prevents their discharge. Clozapine is an effective antipsychotic medication for treatment‐resistant schizophrenia, and its usefulness for aggressive ...
Rikuto Christopher Shinohara, Tomomi Oshima, Takafumi Otsubo, Keita Ariga, Tesshu Ono, Koya Muneoka, Hiroki Umezu, Nobuhiro Mikami   +7 more
doaj   +1 more source