Results 131 to 140 of about 75,341 (263)

Mothering Through the Experiences of Homelessness With a Particular Focus on Child Separation in High‐Income Countries: A Scoping Review

Child &Family Social Work, EarlyView.
ABSTRACT Mothers who experience homelessness represent one of the most vulnerable and marginalized groups, often facing separation from their children as a consequence of housing instability and intersecting challenges. While there is a substantial body of research on parenting in the context of homelessness, little is known about the experience of ...
Olayinka Ariba, Abe Oudshoorn, Cheryl Forchuk, Nadine Wathen, Corinna Easton, Roxanne Isard   +5 more
wiley   +1 more source

Synaptic ultrastructural alterations in human focal cortical dysplasia: Insights from volume electron microscopy

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim, Na‐Young Seo, Seung‐Ki Kim, Jae‐Kyung Won, Yang Hoon Huh, Ji Yeoun Lee, Kea Joo Lee   +6 more
wiley   +1 more source

Meta‐analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape

Epilepsia, EarlyView.
Abstract Objective Despite decades of development in anti‐seizure medications, ~30% of individuals remain refractory to all treatments, and none of the existing therapies are disease modifying. Identifying targets outside the current preclinical paradigm is critically important.
Giovanna L. Durante, Anna L. Tyler, Rod C. Scott, Amanda E. Hernan, J. Matthew Mahoney   +4 more
wiley   +1 more source

Development and Validation of the End‐of‐Life Assessment Tool for Advanced Dementia: A Multi Method Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To develop and validate the End‐of‐Life Care Assessment Tool for Dementia (EoLC‐ATD). Design A methodological study with multiple phases. Methods Five sub‐studies comprising: a review of 90 validated dementia measures to compile an item bank of advanced dementia symptoms; focus groups with registered nurses on advanced dementia symptom ...
Carolyn Bourke, Lynn Chenoweth, Ekavi Georgousopoulou, Anna Williams   +3 more
wiley   +1 more source

Recovery From Anorexia Nervosa: A Concept Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley   +1 more source

Successful utilization of clozapine for a patient with treatment‐resistant schizophrenia after recurrent violent behavior

Neuropsychopharmacology Reports
Background In patients with schizophrenia, violent behavior is a clinically important factor that prevents their discharge. Clozapine is an effective antipsychotic medication for treatment‐resistant schizophrenia, and its usefulness for aggressive ...
Rikuto Christopher Shinohara, Tomomi Oshima, Takafumi Otsubo, Keita Ariga, Tesshu Ono, Koya Muneoka, Hiroki Umezu, Nobuhiro Mikami   +7 more
doaj   +1 more source

Effect of body-oriented psychological therapy on negative symptoms in schizophrenia: a randomized controlled trial [PDF]

, 2006
Priebe, S, Rohricht, F
core   +1 more source

The validity of smartphone data and its relationship to clinical symptomatology and brain biology: an exploratory analysis [PDF]

, 2018
BACKGROUND: Presently, there is very little research on the clinical validity of mental health smartphone application data, its relationship to brain biology, and its ability to inform clinical decisions.
Rizzuto, Conor
core  

Antipsychotic Use Among Intellectually Disabled Individuals With Rare Genetic Variants That Confer Risk for Schizophrenia

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Rare genetic variation can predispose individuals to the development of schizophrenia, with certain genes and copy number variants (CNVs) conferring risk at the exome/genome‐wide level. Despite this strong association, little is known about antipsychotic effectiveness and tolerability among individuals with most of these disorders ...
Mark Ainsley Colijn
wiley   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source