Results 131 to 140 of about 26,546 (243)

The development of positron emission tomography (PET) tracer for glutamate AMPA receptors and its application to human biology and clinics

Psychiatry and Clinical Neurosciences, EarlyView.
Psychiatric and neurological disorders severely compromised patients' quality of life. Despite their urgent needs, the development of diagnostics and therapeutics based on the biological basis has made only little progress. This is due to limited evidence on the biological basis of these disorders in humans. Synapses are fundamental structural units of
Mai Hatano, Hiroki Abe, Takuya Takahashi
wiley   +1 more source

Neural substrates of treatment-resistant schizophrenia and the response to clozapine: A structural MRI study in a clinical setting. [PDF]

PLoS One
Masumo Y, Kanahara N, Otsuka Y, Sudo Y, Ishii T, Sato H, Idemoto K, Komatsu H, Fujita Y, Oda Y, Niitsu T, Hirano Y, Iyo M.   +12 more
europepmc   +1 more source

Intact delay discounting but more optimal reward‐based decisions in anorexia nervosa during an experiential task

Psychiatry and Clinical Neurosciences, EarlyView.
Aims Individuals with anorexia nervosa (AN) have an apparent increased capacity to delay gratification and forgo immediate food rewards in their long‐term pursuit of thinness. Prior research probed this capacity using delay discounting tasks that assess how rapidly the subjective value of rewards decreases as a function of time until receipt.
Fabio Bernardoni, Joseph A. King, Maria Seidel, Martin Schoemann, Nina Kasaeva, Katrin Gramatke, Kerstin Weidner, Veit Roessner, Stefan Scherbaum, Stefan Ehrlich   +9 more
wiley   +1 more source

Personalizing Clozapine in Treatment-Resistant Schizophrenia: The Role of MicroRNA Biomarkers-A Pilot Study. [PDF]

Curr Issues Mol Biol
Sosin DN, Khasanova AK, Illarionov RA, Popova AK, Mirzaev KB, Glotov AS, Mosolov SN, Sychev DA.   +7 more
europepmc   +1 more source

When Regulation Travels: Distrust and Disrespect

Regulation &Governance, EarlyView.
ABSTRACT Endeavoring to avoid the pitfalls of being too trusting of regulated entities' compliance claims, regulators sometimes create regulatory systems with elaborate requirements for verification. But as these accountability and verification regimes attempt to circumvent one set of problems, they may inadvertently create others.
Carol A. Heimer
wiley   +1 more source

"Dream Insertion": A Case Report of a Novel Psychotic Symptom in a Male Inpatient With Treatment Resistant Schizophrenia. [PDF]

Case Rep Psychiatry
Clayton D, Grover S.
europepmc   +1 more source

A Secondary Analysis of Longitudinal Pilot‐Study Data Investigating the Associations Between Health‐Related Quality of Life and Executive Functions in Remitted Major Depressive Disorder and Developments Two‐Years Following Cognitive Training

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT Major depressive disorder (MDD) is associated with reduced quality of life and relapse risk. However, few studies have investigated how quality of life is associated with cognitive deficits following MDD and is affected by cognitive training.
Eivind Haga Ronold, Silje Klundelien Storfossen, Marta Vikingstad Vignes, Åsa Hammar   +3 more
wiley   +1 more source

How do physiological networks respond to normobaric hypoxia and isometric exercise?

Experimental Physiology, EarlyView.
Abstract The dynamics of physiological systems are impacted by both exercise and hypoxia. Network models can be used to map the interactions between various physiological components in environmental physiology and exercise using the concepts of information theory.
Danilo Bondi, Cecilia Morandotti, Salvatore Annarumma, Carmen Santangelo, Tiziana Pietrangelo, Stefania Fulle, Vittore Verratti   +6 more
wiley   +1 more source

Psychobiotics and the microbiota–gut–brain axis: Emerging paradigms in mental health modulation

Experimental Physiology, EarlyView.
Abstract The global rise in mental health conditions has prompted interest in interventions that act beyond conventional psychopharmacology. Psychobiotics, broadly understood as live microorganisms or microbe‐derived products that interact with the microbiota–gut–brain axis, have been suggested to exert neuroactive effects through neural, immune ...
Amir Arsalan Ghahari, Mehrdad Nourizadeh, Mehrdad SalekShahabi, Shaghayegh Davari, Saeid Mohammadzadeh Mounesyar   +4 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source