Results 171 to 180 of about 75,341 (263)
Personalizing Clozapine in Treatment-Resistant Schizophrenia: The Role of MicroRNA Biomarkers-A Pilot Study. [PDF]
Sosin DN +7 more
europepmc +1 more source
Inverse Association Between Betel Quid Use and Diabetes in Rural Bangladesh
ABSTRACT Objectives Betel quid is used as a mild stimulant in many parts of South and East Asia and the Pacific. In observational studies, its use has been associated with elevated risk for diabetes, but studies in animal models suggest some component(s) of betel quid could reduce risk.
Kristin K. Sznajder +9 more
wiley +1 more source
"Dream Insertion": A Case Report of a Novel Psychotic Symptom in a Male Inpatient With Treatment Resistant Schizophrenia. [PDF]
Clayton D, Grover S.
europepmc +1 more source
Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu +1 more
wiley +1 more source
Executive Impairment in Huntington's Disease: Insights From a Systematic Review of the Literature
Executive dysfunction in Huntington's disease follows a selective, stage‐dependent pattern, with early deficits in psychomotor speed, cognitive flexibility, inhibition, and working‐memory updating. Progression is associated with broader impairments in planning and attention.
Simone Migliore +4 more
wiley +1 more source
ABSTRACT Dopamine (DA) plays a vital role as a neurotransmitter in the central nervous system (CNS), and its accurate quantification is essential for diagnosing neurological disorders. However, selective and sensitive detection of DA in complex biological matrices remains a challenge due to interference from coexisting biomolecules.
N. I. Nayem +7 more
wiley +1 more source
Abstract Objective This study aims to investigate the causal relationship between cathepsins and epilepsy, using Mendelian randomization (MR) and mediation analysis. Methods Publicly accessible summary statistics on epilepsy were obtained from FinnGen and the International League Against Epilepsy Consortium.
Huaiyu Sun +7 more
wiley +1 more source
Abstract Introduction Long‐acting injectable (LAI) cabotegravir/rilpivirine (CAB/RPV) represents a breakthrough in HIV treatment. However, understanding how to optimize real‐world service delivery and user experiences among people with HIV (PWH) remains limited. Methods Between August 2022 and December 2024, we conducted semi‐structured interviews with
Xavier A. Erguera +17 more
wiley +1 more source
Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin +12 more
wiley +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source

