Results 31 to 40 of about 75,341 (263)

Generation of ultra-treatment-resistant schizophrenia patient-derived induced pluripotent stem cell line UJSi002-A

open access: yesStem Cell Research, 2022
Schizophrenia is a chronic, serious and disabling mental disorder. Most patients can effectively control their condition through drug treatment, but there are still some patients who are difficult to gain benefits from drug treatment.
Jing Sun   +7 more
doaj   +1 more source

A contextual behavioral approach to the study of (persecutory) delusions [PDF]

open access: yes, 2016
Throughout the past century the topic of delusions has mainly been studied by researchers operating at the mental level of analysis. According to this perspective, delusional beliefs, as well as their emergence and persistence, stem from an interplay ...
Hughes, Sean Joseph   +2 more
core   +3 more sources

Combination of clozapine, cariprazine and fluoxetine in treatment-resistant schizophrenia patient with prominent negative symptoms: A Case report

open access: yesEuropean Psychiatry, 2022
Introduction Despite pharmacological advances in the treatment of schizophrenia, significant number of patients are still treatment-resistant. Clozapine is recommended as first-line treatment for treatment-resistant schizophrenia (TRS) in guidelines ...
I. Everte, A. Pamše-Romāne, M. Taube
doaj   +1 more source

Minimal-medication approaches to treating schizophrenia [PDF]

open access: yes, 2009
UK guidelines for treating people diagnosed with schizo phrenia currently emphasise the primacy of antipsychotic medication, with or without psycho-socially based interventions as circumstances dictate.
Aderhold   +40 more
core   +1 more source

Electroconvulsive Therapy for Treatment-Resistant Schizophrenia [PDF]

open access: yesSchizophrenia Bulletin, 2019
Electroconvulsive therapy (ECT) involves the induction of a seizure by the administration of an electrical stimulus via electrodes usually placed bilaterally on the scalp and was introduced as a treatment for schizophrenia in 1938. However, ECT is a controversial treatment with concerns about long-term side effects such a memory loss.
Diarmid J M, Sinclair   +5 more
openaire   +4 more sources

Strategies in clozapine-resistant schizophrenia: A literature review

open access: yesJournal of Mental Health and Human Behaviour, 2016
Treatment resistance to what is often deemed the last line of schizophrenia treatment, clozapine, is a burgeoning problem in psychiatric practice, with estimates of clozapine resistance standing at 40–70% of the treated population.
Ganesh Kundadak Kudva   +1 more
doaj   +1 more source

Occupational therapy for people with psychotic conditions in community settings: a pilot randomized controlled trial [PDF]

open access: yes, 2008
OBJECTIVES: To investigate the effectiveness of a long established intervention, occupational therapy for people with psychotic conditions, and to inform future research designs. DESIGN: A pilot randomized controlled trial.
Andreasen NC   +13 more
core   +1 more source

Association of DRD2, DRD4 and COMT genes variants and their gene-gene interactions with antipsychotic treatment response in patients with schizophrenia

open access: yesBMC Psychiatry, 2023
Antipsychotic drugs are the first line of treatment in schizophrenia; although antipsychotic responses indicate a wide interindividual variety in patients with schizophrenia.
Narges Taheri   +4 more
doaj   +1 more source

Combined use of clozapine and cariprazine in treatment-resistant schizophrenia, is it a good choice?

open access: yesEuropean Psychiatry, 2021
Introduction Treatment-resistant schizophrenia (TRS) affects 30% of people with a diagnosis of schizophrenia, and is defined as nonresponse to at least two trials of antipsychotic medication of adequate dose and duration. Clozapine is the only evidence-
H. Becerra Darriba
doaj   +1 more source

Sex differences in plasma clozapine and norclozapine concentrations in clinical practice and in relation to body mass index and plasma glucose concentrations: a retrospective survey [PDF]

open access: yes, 2015
Background Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attaining 17 % higher plasma clozapine ...
Anderson, Simon G.   +7 more
core   +2 more sources

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