Results 31 to 40 of about 26,546 (243)
Combined use of clozapine and cariprazine in treatment-resistant schizophrenia, is it a good choice?
European Psychiatry, 2021 Introduction Treatment-resistant schizophrenia (TRS) affects 30% of people with a diagnosis of schizophrenia, and is defined as nonresponse to at least two trials of antipsychotic medication of adequate dose and duration. Clozapine is the only evidence-
H. Becerra Darriba
doaj +1 more source
Thyroid function test abnormalities in treatment-resistant schizophrenia
Psychiatry and Clinical Psychopharmacology, 2021 Objective: The relationship between thyroid dysfunction and mood disorders is well recognized. Thyroid function abnormalities are bad prognostic factors in mood disorders, and augmentation with thyroid hormone has therapeutic efficacy in treatment ...
Ertac Sertac Orsel +4 more
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A Case Report: Treatment Resistant Schizophrenia [PDF]
Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2004 Clinicians define resistance to treatment of schizophrenia, as a failure including functional and psyhcosocial dimensions despite adequate dosage, duration and treatment consistency.
Gamze Sönmez +5 more
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BMC Psychiatry, 2022 Background Clozapine has the greatest efficacy for treatment-resistant schizophrenia (TRS), even though its underutilization is not uncommon across different countries.
Leeba Rezaie +4 more
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Clozapine prescription trends in Brazil in the last decade
Brazilian Journal of Psychiatry, 2022 Objective: Clozapine is a second-generation antipsychotic indicated for treatment-resistant schizophrenia. Studies in several countries have shown a low rate of clozapine use despite the fact that approximately 30% of schizophrenia cases are treatment ...
Raffael Massuda +7 more
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Boron‐Doped Nano‐Crystalline Coated Carbon Fibers for Phasic Dopamine Sensing
Advanced Healthcare Materials, EarlyView.This uniform coating presents a mix of graphitic and diamond‐like carbon to create a mechanically and electrically robust alternative for the electrochemical detection of dopamine. The electrodes in this work possess the equivalent sensitivity to the state‐of‐the‐art FSCV dopamine detecting electrodes, whilst demonstrating an ability to withstand ...
Simon J. Higham +19 more
wiley +1 more source
Treatment-Resistant Schizophrenia and Staff Rejection [PDF]
Schizophrenia Bulletin, 1999 This study examined the relationship between characteristics of patients suffering from treatment-refractory schizophrenia and staff rejection and criticism. Subjects were 30 inpatients with treatment-resistant schizophrenia and the 29 staff members treating them.
U, Heresco-Levy +4 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source