Results 81 to 90 of about 4,217,894 (213)

Diagnosis and management of antiretroviral-therapy failure in resource-limited settings in sub-Saharan Africa: challenges and perspectives. [PDF]

, 2010
Despite the enormous progress made in scaling up antiretroviral therapy (ART) in sub-Saharan Africa, many challenges remain, not least of which are the identification and management of patients who have failed first-line therapy. Less than 3% of patients
Akileswaran, Andreas Jahn, Anthony D Harries, Badri, Bierman, Boulle, Boulle, Colebunders, Elliott, Erik J Schouten, Ferradini, Gazzard, Gupta, Hammer, Harries, Harries, Hosseinipour, Joep J van Oosterhout, Johannessen, Johnson, Kamya, Kantor, Keiser, Kelita Kamoto, Kitahata, Kouanfack, Kuhn, Lawn, Lawn, Ledergerber, Libamba, Lockman, Maldonado, Mee, Mills, Mina C Hosseinipour, Moore, Mwaba, Orrell, Phillips, Pujades-Rodriguez, Reynolds, Rony Zachariah, Samb, Sawe, Steven D Reid, Swindells, Tuboi, Uy, van Oosterhout, Vic Arendt, Walmsley, Weiser, Wester, Wilson, Yu, Zachariah, Zengani Chirwa   +57 more
core   +2 more sources

Outcome specific optimal systolic blood pressure targets in high risk patients, balancing cardiovascular benefits, renal risks, and cancer prevention: meta-analysis of randomised controlled trials

BMJ Medicine
Objective To directly compare the efficacy and safety of different intensive systolic blood pressure targets (<120 or <130 mm Hg) versus usual care on cardiovascular and renal outcomes.Design Meta-analysis of randomised controlled trials.Data ...
Yuanyuan Zhang, Yu Huang, Yiwei Zhang, Xianhui Qin, Yanjun Zhang, Sisi Yang, Xiaoqin Gan, Fan Fan Hou, Yiting Wu   +8 more
doaj   +1 more source

The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings.

, 2006
WHO has proposed a public-health approach to antiretroviral therapy (ART) to enable scaling-up access to treatment for HIV-positive people in developing countries, recognising that the western model of specialist physician management and advanced ...
Crowley, Siobhan, De Cock, Kevin, Ekpini, René, Gilks, Charles F, Gove, Sandy, Guerma, Teguest, Perriens, Jos, Souteyrand, Yves, Sutherland, Don, Vitoria, Marco   +9 more
core   +1 more source

Indole-3-propionic acid exacerbates cisplatin-induced chronic kidney disease through the AHR/NF-κB signaling pathway

iScience
Summary: Cisplatin is a commonly used chemotherapy agent for treating various solid tumors, but its clinical application is limited by nephrotoxicity.
Qian Wang, Jie Chen, Huini Chen, Dongning Liang, Hong Zhou, Juanjuan Chen, Yuan Gui, Fang Yao, Yudan Chen, Xi Zeng, Yaxiang Ma, Dong Zhou, Haiyan Fu   +12 more
doaj   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science
Liver fat content (LFC) is a key biomarker for cardiovascular‐kidney‐metabolic (CKM), yet noninvasive assessment remains challenging. It aims to develop a plasma proteomic‐based LFC score to predict MRI‐derived proton density fat fraction (MRI‐PDFF ...
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
doaj   +1 more source

Outcomes and readmissions after cardiac surgery in patients with chronic steroid use: a nationwide propensity score matched analysis

Journal of Cardiothoracic Surgery
Background We characterized index admission outcomes and 30-day readmissions after cardiac surgery in patients with chronic steroid use (CSU) in a large national administrative database.
Jean-Luc A. Maigrot, Guangjin Zhou, Siran M. Koroukian, Nicholas Schiltz, Edward G. Soltesz   +4 more
doaj   +1 more source

Combined Prognostic Impact of Low Muscle Mass and Hypoalbuminemia in Patients Hospitalized for Heart Failure: A Retrospective Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Sarcopenia and hypoalbuminemia have been identified as independent predictors of increased adverse outcomes, including mortality and readmissions, in hospitalized older adults with acute decompensated heart failure (ADHF).
Saeid Mirzai, Kunaal S. Sarnaik, Ian Persits, Pieter Martens, Jerry D. Estep, Po‐Hao Chen, W. H. Wilson Tang   +6 more
doaj   +1 more source

Remote operation of an orbital maneuvering vehicle in simulated docking maneuvers [PDF]

Simulated docking maneuvers were performed to assess the effect of initial velocity on docking failure rate, mission duration, and delta v (fuel consumption).
Brody, Adam R.
core   +1 more source

HIV-associated multi-centric Castleman’s disease with multiple organ failure: cuccessful treatment with rituximab [PDF]

, 2010
Introduction: Multicentric Castleman's Disease (MCD), a lymphoproliferative disorder associated with Human Herpes Virus-8 (HHV-8) infection, is increasing in incidence amongst HIV patients.
Agarwal, B, Cleverley, JR, Cwynarski, K, Doyle, T, Isaacson, PG, Johns, RH, Lipman, M, Shaw, S   +7 more
core  

Epidemiology of injuries at the first transplant football world cup

Frontiers in Sports and Active Living
IntroductionRecreational football is widely recognized as a health-promoting activity, with proven long-term benefits for physical and mental well-being.
Valentina Totti, Filippo Ferrari, Simone Paltrinieri, Giovanni Vitale, Giovanni Mosconi, Alessandro Nanni Costa, Gianluigi Sella, Maria Cristina Morelli, Paolo Caraceni, Paolo Caraceni, Giulio Sergio Roi   +10 more
doaj   +1 more source