Results 131 to 140 of about 17,612,218 (346)

Outcome of children with brain stem gliomas after treatment with 7800 cGy of hyperfractionated radiotherapy. A childrens cancer group phase 1/11 trial [PDF]

, 1994
Roger J. Packer, James M. Boyett, Robert A. Zimmerman, A. Leland Albright, Allen M. Kaplan, Lucy B. Rorke, Michael T. Selch, Joel M. Cherlow, Jonathan L. Finlay, William M. Wara   +9 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Depressed Skull Fracture: Outcome of Surgical Treatment

, 1970
M Zahed Hossain, MS Mondle, Martha Hoque
openalex   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Presentation and Immediate Outcome of Surgical Treatment of Patients with Carcinoma of the Stomach - A Comparative Study between Young and Elderly patients

, 1970
SA Chowdhury, MM Hussain, JU Ahmed
openalex   +2 more sources

Diagnosis, treatment, and outcome of follicular thyroid carcinoma [PDF]

, 1994
John V. Collin, Orlo H. Clark, Geoffrey T. Emerick, Quan‐Yang Duh, Allan Siperstein, Gerard N. Burrow   +5 more
openalex   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Psychosocial outcome in a randomized surgical trial for treatment of primary breast cancer

, 1988
Margaret Kemeny, David K. Wellisch, Wendy S. Schain   +2 more
openalex   +1 more source

A meta‐analysis of the relation between therapeutic alliance and treatment outcome in eating disorders

International Journal of Eating Disorders, 2017
Tiffany A. Graves, Nassim Tabri, H. Thompson-Brenner, D. Franko, Kamryn T. Eddy, Stephanie Bourion-Bedes, A. Brown, Michael J. Constantino, C. Flückiger, Sarah Forsberg, Leanna Isserlin, J. Couturier, Gunilla Paulson Karlsson, Johannes Mander, M. Teufel, James E Mitchell, R. Crosby, Claudia Prestano, Dana A. Satir, Susan G Simpson, Richard Sly, J. Lacey, Colleen Stiles-Shields, G. Tasca, G. Waller, S. Zaitsoff, R. Rienecke, D. Le Grange, J. Thomas   +28 more
semanticscholar   +1 more source