Results 101 to 110 of about 27,683,163 (345)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Substitution of D701N in the PB2 protein could enhance the viral replication and pathogenicity of Eurasian avian-like H1N1 swine influenza viruses

Emerging Microbes and Infections, 2018
Eurasian avian-like H1N1 (EA H1N1) swine influenza viruses (SIVs) have become predominant in pig populations in China and have recently been reported to have the most potential to raise the next pandemic in humans.
Suli Liu, Wenfei Zhu, Zhaomin Feng, Rongbao Gao, Junfeng Guo, Xiyan Li, Jia Liu, Dayan Wang, Yuelong Shu   +8 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Characterizing and configuring motorized wedge for a new generation telecobalt machine in a treatment planning system

Journal of Medical Physics, 2007
A new generation telecobalt unit, Theratron Equinox-80, (MDS Nordion, Canada) has been evaluated. It is equipped with a single 60-degree motorized wedge (MW), four universal wedges (UW) for 150, 300, 450 and 600.
Kinhikar Rajesh, Sharma Smriti, Upreti Rituraj, Tambe Chandrashekhar, Deshpande Deepak   +4 more
doaj  

Deregulated MicroRNA-21 Expression in Monocytes from HIV-Infected Patients Contributes to Elevated IP-10 Secretion in HIV Infection

Frontiers in Immunology, 2017
Persistent activation and inflammation impair immune response and trigger disease progression in HIV infection. Emerging evidence supports the supposition that excessive production of interferon-inducible protein 10 (IP-10), a critical inflammatory ...
Xian Wu, Xian Wu, Le-Le Zhang, Le-Le Zhang, Lin-Bo Yin, Lin-Bo Yin, Ya-Jing Fu, Ya-Jing Fu, Yong-Jun Jiang, Yong-Jun Jiang, Hai-Bo Ding, Hai-Bo Ding, Zhen-Xing Chu, Zhen-Xing Chu, Hong Shang, Hong Shang, Zi-Ning Zhang, Zi-Ning Zhang   +17 more
doaj   +1 more source

Evaluation of a dedicated brain metastases treatment planning optimization for radiosurgery: a new treatment paradigm?

Radiation Oncology, 2016
To investigate the feasibility of a novel dedicated treatment planning solution, to automatically target multiple brain metastases with a single isocenter and multiple inversely-optimized dynamic conformal arcs (DCA), and to benchmark it against the well-
T. Gevaert, F. Steenbeke, L. Pellegri, B. Engels, N. Christian, M. Hoornaert, D. Verellen, C. Mitine, M. de Ridder   +8 more
semanticscholar   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Real world report: PSMA-PET/CT-guided TNM restaging and its consequences for treatment planning in prostate cancer

Frontiers in Oncology
ObjectiveThis study aimed to explore the effect of prostate-specific membrane antigen (PSMA) positron emission tomography and computed tomography (PET/CT) on clinical TNM (cTNM) staging assessment and treatment decision-making in prostate cancer ...
Han Chen, Peng Xian, Nan Liu, Yanping Song   +3 more
doaj   +1 more source

Automatic treatment planning improves the clinical quality of head and neck cancer treatment plans

Clinical and Translational Radiation Oncology, 2016
Highlights • Autoplan can produce clinically better VMAT radiotherapy plans for H&N cancer.• Autoplan plans have similar target coverage with significant sparing of OAR.• With a template the TPS can automatically create better plans than manually created
C. Hansen, A. Bertelsen, I. Hazell, R. Zukauskaite, N. Gyldenkerne, J. Johansen, J. Eriksen, C. Brink   +7 more
semanticscholar   +1 more source

Hyperthermia treatment planning: Clinical application and ongoing research

, 2020
Hyperthermia, i.e. heating tumour tissue to 40-43°C, is applied clinically to enhance the effectiveness of chemotherapy and radiotherapy. Treatment planning can be a very valuable tool to improve clinical treatment quality.
J. Crezee, Crezee, J., H.P. Kok, Kok, H. P.   +3 more
core   +1 more source