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Migraine and treatment-resistant depression

2023
Migraine and major depressive disorders (MDD) or treatment resistant depression (TRD) represent a significant global burden and are often comorbid, further complicating diagnosis and treatment. Epidemiological studies have demonstrated a bidirectional relationship between migraine and MDD/TRD, with patients suffering from one disorder exhibiting a ...
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Overview of treatment-resistant depression

2023
Patients with major depressive disorder (MDD) often exhibit an inadequate treatment response or failure to achieve remission following treatment with antidepressant drugs. Treatment-resistant depression (TRD) is proposed to identify this clinical scenario.
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Medication Options in the Treatment of Treatment-Resistant Depression

Australian & New Zealand Journal of Psychiatry, 2004
Aim: Less than half of those suffering major depressive episodes achieve remission with the first antidepressant provided and one-third of all patients suffering depression have a chronic condition. Clinical experience indicates that a substantial proportion of patients suffer treatment-resistant depression (TRD)
Pridmore, Saxby, Turnier-Shea, Yvonne
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Clomipramine augmentation in treatment-resistant depression

Depression and Anxiety, 1997
In depression that is resistant to tricyclic antidepressant (TCA) therapy, the substitution of a selective serotonin re-uptake inhibitor (SSRI), clomipramine, or a monoamine oxidase (MAO) inhibitor has been recommended. However, adding an additional antidepressant medication from a different drug class may produce even more rapid efficacy.
J D, Amsterdam   +2 more
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TREATMENT-RESISTANT BIPOLAR DEPRESSION

Psychiatric Clinics of North America, 1996
Patients with treatment-resistant bipolar depression require careful management, which takes into account the life-threatening potential of their depression and the risk of iatrogenic mania. Because there are few data specific to treatment of bipolar depression, much of the approach to bipolar depression is derived from experience with unipolar ...
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Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression

New England Journal of Medicine, 2022
Charles Debattista   +2 more
exaly  

Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression

New England Journal of Medicine, 2023
Murat Altinay   +2 more
exaly  

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