Results 261 to 270 of about 766,404 (301)

ECT in Treatment-Resistant Depression

American Journal of Psychiatry, 2012
Electroconvulsive therapy (ECT), which has been in use for 75 years, is an important treatment for severe and treatment-resistant depression. Although it is acknowledged as the most effective acute treatment for severe mood and psychotic disorders, it remains controversial because of misperceptions about its use and lack of familiarity among health ...
Charles H, Kellner, Robert M, Greenberg, James W, Murrough, Ethan O, Bryson, Mimi C, Briggs, Rosa M, Pasculli   +5 more
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Treatment-resistant depression: molecular mechanisms and management

Molecular Biomedicine
Due to the heterogeneous nature of depression, the underlying etiological mechanisms greatly differ among individuals, and there are no known subtype-specific biomarkers to serve as precise targets for therapeutic efficacy. The extensive research efforts
Mayanja M. Kajumba, Angelina Kakooza-Mwesige, N. Nakasujja, Deborah C. Koltai, T. Canli   +4 more
semanticscholar   +1 more source

Treatment for Therapy-Resistant Depression

Psychopathology, 2010
Thanks to progress in the diagnosis and treatment of depression it is now possible for most cases to be treated on an out-patient basis. Only 15–20% of patients require hospitalisation, most of them because their depression has proved resistant to therapy.
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Strategies for treatment-resistant depression

Clinical Cornerstone, 1999
Clinical depression is a common disorder with serious implications that is often misdiagnosed or underestimated. More than 50% of suicides are associated with a major depressive disorder, and depression can adversely impact a variety of other medical conditions.
P G, Janicak, B, Martis
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Treatment resistant depression in elderly

2023
Treatment refractory depression (TRD) in the elderly is a common psychiatric disorder with high comorbidity and mortality. Older adults with TRD often have complicated comorbidities and several predisposing risk factors, which may lead to neuropsychiatric dysfunction and poor response to treatment.
Sheng-Chiang, Wang, Jennifer S, Yokoyama, Nian-Sheng, Tzeng, Chia-Fen, Tsai, Mu-N, Liu   +4 more
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Targeting Treatment-Resistant Depression

Journal of Pharmacy Practice, 2011
Only 50% of depressed patients achieve remission of symptoms after 2 trials of antidepressants. Therefore one half of patients are considered treatment resistant. Studies have shown that with each failed antidepressant, chances of remission continue to decline.
Monica, Mathys, Brian G, Mitchell
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Esketamine for Treatment-Resistant Depression

JAMA Psychiatry
To the Editor Janik et al reported a positive trial of esketamine monotherapy for treatment-resistant depression. However, the lead-in design and functional unblinding could have biased treatment estimates. The 4-week double-blind phase was preceded by a lead-in phase of up to 7 weeks, during which time antidepressant medication was discontinued ...
Cristea I. A., Plöderl M., Naudet F.
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Esketamine for treatment-resistant depression

Drug and Therapeutics Bulletin, 2020
Generic name: Esketamine hydrochloride Brand name: Spravato Formulation: 28mg in 0.2ml nasal spray solution Market Authorisation holder: Janssen-Cilag International NV Indication: Treatment resistant
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A systematic review and meta-analysis of the efficacy of intravenous ketamine infusion for treatment resistant depression: January 2009 - January 2019.

Journal of Affective Disorders, 2020
BACKGROUND Sub-anaesthetic administration of ketamine is an emerging practice in patients presenting treatment resistant depression (TRD), however several outstanding questions have yet to be answered.
W. Marcantoni, Bertine Sandra Akoumba, M. Wassef, Julie Mayrand, H. Lai, S. Richard-Devantoy, S. Beauchamp   +6 more
semanticscholar   +1 more source

Migraine and treatment-resistant depression

2023
Migraine and major depressive disorders (MDD) or treatment resistant depression (TRD) represent a significant global burden and are often comorbid, further complicating diagnosis and treatment. Epidemiological studies have demonstrated a bidirectional relationship between migraine and MDD/TRD, with patients suffering from one disorder exhibiting a ...
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