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Modeling treatment-resistant depression [PDF]
Neuropharmacology, 2011 Depression is a polygenic and highly complex psychiatric disorder that is currently a major burden on society. Depression is highly heterogeneous in presentation and frequently exhibits high comorbidity with other psychiatric and somatic disorders. Commonly used treatments, such as selective serotonin reuptake inhibitors (SSRIs), are not ideal since ...
Benjamin Adam, Samuels +8 more
openaire +2 more sources
Is treatment resistant depression a different subtype of depression?
European Psychiatry, 2021 Major depression is a serious, disabling, often chronic or recurrent mental disorder affecting over 350 million people worldwide. Treatment of major depression is now conceptualized as proceeding through three phases: the acute phase, the continuation ...
A. Fiorillo
doaj +1 more source
Use of pharmacotherapies for treatment resistant depression in finland: A nationwide cohort study
European Psychiatry, 2021 Introduction There is a lack of knowledge on utilized pharmacotherapies for treatment resistant depression (TRD). Objectives To investigate the courses of treatment of TRD.
H. Taipale +4 more
doaj +1 more source
Frontiers in Psychology, 2019 The current study investigated the comprehension of mindfulness-based cognitive behavioral therapy (MBCT) by patients with resistant depression at the Psychiatry Institute of the Federal University of Rio de Janeiro, Brazil.
Michele F. Rodrigues +7 more
doaj +1 more source
Accelerated intermittent theta burst stimulation for suicide risk in therapy-resistant depressed patients : a randomized, sham-controlled trial [PDF]
, 2016 Objectives: We aimed to examine the effects and safety of accelerated intermittent Theta Burst Stimulation (iTBS) on suicide risk in a group of treatment-resistant unipolar depressed patients, using an extensive suicide assessment scale.
Audenaert, Kurt +5 more
core +3 more sources
A study of remitted and treatment-resistant depression using MMPI and including pessimism and optimism scales. [PDF]
PLoS ONE, 2014 The psychological aspects of treatment-resistant and remitted depression are not well documented.We administered the Minnesota Multiphasic Personality Inventory (MMPI) to patients with treatment-resistant depression (n = 34), remitted depression (n = 25),
Masatoshi Suzuki +5 more
doaj +1 more source
PLoS ONE, 2020 Objective The economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non–treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li +8 more
doaj +2 more sources
Treatment of resistant depression : a pilot study assessing the efficacy of a tDCS-mindfulness program compared with a tDCS-relaxation program [PDF]
, 2019 Background: This pilot study explores a therapeutic setting combining transcranial direct current stimulation (tDCS) and mindfulness-based cognitive therapy (MBCT) for patients with drug-resistant depression.
Campanella, Salvatore +5 more
core +2 more sources
Do baseline anxiety symptoms impact response to IV Ketamine in treatment resistant depression?
Journal of Affective Disorders Reports, 2021 Objective: In a retrospective study, we analyzed if anxious depression impacts outcomes in patients with treatment resistant depression (TRD) receiving IV Ketamine infusions at an academic center Ketamine clinic.
Zoe Schreiber +7 more
doaj +1 more source
Treatment Resistant Depression [PDF]
American family physician, 2009 Up to two thirds of patients with major unipolar depression will not respond to the first medication prescribed. Depression may be considered resistant to treatment when at least two trials with antidepressants from different pharmacologic classes (adequate in dose, duration, and compliance) fail to produce a significant clinical improvement.
Philip G. Janicak, Sheila M. Dowd
+7 more sources