Results 41 to 50 of about 93,603 (306)

Lamotrigine in the treatment of schizoaffective disorder [PDF]

, 1998
There is accumulating evidence for the efficacy of lamotrigine in the treatment of bipolar disorder, including bipolar depression, both as monotherapy and in combination with sodium valproate.
Grunze, Heinz, Erfurth, Andreas, Walden, Jörg   +2 more
core   +1 more source

Suicidality in Treatment-Resistant Depression Patients

European Psychiatry, 2023
Introduction Depression and treatment-resistant depression (RD) are associated with suicidal behavior (SB) at a higher rate. Objectives 1) determination prevalence of RD in district outpatient psychiatric сlinics (i.e., dispensaries) and the socio ...
E. B. Lyubov, N. D. Semenova
doaj   +1 more source

Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections. [PDF]

, 2010
Despite significant research efforts aimed at understanding the neurobiological underpinnings of psychiatric disorders, the diagnosis and the evaluation of treatment of these disorders are still based solely on relatively subjective assessment of ...
Brittain, Claire, Holsboer, Florian, Alexander, R. C., Inga Prokopenko, Robert C Alexander, Rujescu, D., Enrico Domenici, Bullmore, E., Giegling, Ina, Tozzi, F., Claire Brittain, Prokopenko, I, Turck, C., Ina Giegling, Merlo-Pich, E, Middleton, Lefkos, Wille, DR, Tozzi, Federica, Domenici, Enrico, Merlo-Pich, Emilio, Willé, David R., Miller, Sam, Astrid McKeown, Domenici, E, Edward T Bullmore, Middleton, L, Bullmore, ET, Alexander, Robert C., Tozzi, F, Robert C. Alexander, Holsboer, F, Emilio Merlo-Pich, Merlo-Pich, E., Rujescu, D, Sam Miller, McKeown, A, Middleton, L., Christoph W Turck, Federica Tozzi, Enrico Domenici, Prokopenko, I., Wille, D., David R Willé, Pierandrea Muglia, Giegling, I, McKeown, A., Turck, CW, Holsboer, F., Dan Rujescu, Bullmore, Edward T., Wille, D. R., Brittain, C, Christoph W. Turck, McKeown, Astrid, Muglia, P, Alexander, RC, Prokopenko, Inga, Miller, S., Giegling, I., Alexander, R., Muglia, P., Bullmore, E. T., David R. Willé, Edward T. Bullmore, Muglia, Pierandrea, Turck, C. W., Florian Holsboer, Brittain, C., Miller, S, Lefkos Middleton, Domenici, E., Turck, Christoph W., Rujescu, Dan   +72 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Functional connectivity between the amygdala and subgenual cingulate gyrus predicts the antidepressant effects of ketamine in patients with treatment‐resistant depression

Neuropsychopharmacology Reports, 2021
Aim Approximately one‐third of patients with major depressive disorder develop treatment‐resistant depression. One‐third of patients with treatment‐resistant depression demonstrate resistance to ketamine, which is a novel antidepressant effective for ...
Tomoyuki Nakamura, Masaru Tomita, Naoki Horikawa, Masatoshi Ishibashi, Ken Uematsu, Teruyuki Hiraki, Toshi Abe, Naohisa Uchimura   +7 more
doaj   +1 more source

A model for the management of difficult to treat depression

European Psychiatry, 2021
In this presentation a model for the management of difficult to treat depression (DTD) will be presented based upon a recently published international consensus statement (McAllister-Williams et al. 2020 Journal of Affective Disorders 267:264-282).
H. Mcallister-Williams
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Predictors of prospective suicide attempts in a group at risk of personality disorder following self-poisoning

Frontiers in Psychiatry, 2023
BackgroundPatients with personality disorder (PD) are at risk for suicidal behavior and are frequently admitted for this reason to emergency departments.
Lionel Cailhol, Mariève Marcoux, Anjali Mathur, Antoine Yrondi, Philippe Birmes   +4 more
doaj   +1 more source

Interpersonal psychotherapy and mirtazapine versus mirtazapine alone in treatment resistant depressed patients with sequential functional brain scans of dopamine D2 receptors with IBZM spect [PDF]

, 2007
Twenty DSM-IV major depressed patients who had not responded to at least one previous trial of antidepressant therapy at an adequate dose and duration agreed to participate in this study. They were randomly assigned to receive either mirtazapine (30-45mg)
Robinson, Elizabeth
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