Results 51 to 60 of about 93,603 (306)

Pharmacological treatment of depression in older people

open access: yes, 2006
In the light of recent National Institute for Clinical Excellence (NICE) and Committee for the Safety of Medicines (CSM) guidance we discuss the importance of the diagnosis of depression in old age and review pharmacological interventions.
Wattis, John   +2 more
core   +1 more source

Neuromodulation for treatment-resistant depression [PDF]

open access: yesF1000 Medicine Reports, 2012
Treatment-resistant depression affects at least 1-3% of the US population. This article reviews the current state of focal neuromodulation therapies for treatment-resistant depression, focusing on those treatments published clinical data. These include transcranial magnetic stimulation, transcranial direct current stimulation, magnetic seizure therapy,
Holtzheimer, Paul E., Mayberg, Helen S.
openaire   +2 more sources

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar   +3 more
wiley   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

open access: yesArthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King   +10 more
wiley   +1 more source

Clinical and biological markers of electroconvulsive therapy effectiveness: a narrative review

open access: yesTranslational Psychiatry
Electroconvulsive therapy (ECT) is the most effective treatment for several particularly severe or pharmacotherapy-resistant psychiatric disorders, and a growing number of studies have investigated factors influencing the effectiveness of ECT.
David Zilles-Wegner   +3 more
doaj   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles   +14 more
wiley   +1 more source

Treatment-Resistant Bipolar Depression: Therapeutic Trends, Challenges and Future Directions

open access: yes, 2022
Omar H Elsayed,1 Mete Ercis,2 Mehak Pahwa,1 Balwinder Singh2 1Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville, KY, USA; 2Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USACorrespondence ...
Elsayed OH, Ercis M, Pahwa M, Singh B
core  

Moderators of the Effects of Exercise and Manual Therapy for People With Knee and Hip Osteoarthritis: A Secondary Analysis of a Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to investigate potential moderators influencing the effects of manual therapy and exercise therapy on pain and functional outcomes in individuals with knee and/or hip osteoarthritis, using data from the MOA trial. This is a secondary analysis of data from the MOA trial that compares the clinical effectiveness of manual ...
Daniel Cury Ribeiro   +2 more
wiley   +1 more source

Acceptance and Commitment Therapy group for treatment-resistant participants: a randomized controlled trial

open access: yes, 2014
Acceptance and Commitment Therapy (ACT) is a theoretically coherent approach addressing common processes across a range of disorders. The aim of this study was to investigate the effectiveness of a group-based ACT intervention for ‘treatment-resistant ...
Clarke, Sue   +7 more
core   +1 more source

A review of the conceptualisation and risk factors associated with treatment-resistant depression [PDF]

open access: yes, 2017
Major depression does not always remit. Difficult-to-treat depression is thought to contribute to the large disease burden posed by depression. Treatment-resistant depression (TRD) is the conventional termfor nonresponse to treatment in individuals with ...
Murphy, JA   +10 more
core   +1 more source

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