Results 31 to 40 of about 766,404 (301)
TREATMENT ALGORITHMS IN TREATMENT-RESISTANT DEPRESSION
Psychiatric Clinics of North America, 1996 When faced with a patient having treatment-resistant depression, it is essential to maintain a systematic approach to diagnosis and treatment: 1. Consider the presence of comorbid medical or psychiatric illness that may contribute to or cause the refractory state 2. Determine the affective subtype of depression (e.g., unipolar vs. phenotypic variant of
J D, Amsterdam, M, Hornig-Rohan
openaire +2 more sources
Modeling treatment-resistant depression [PDF]
Neuropharmacology, 2011 Depression is a polygenic and highly complex psychiatric disorder that is currently a major burden on society. Depression is highly heterogeneous in presentation and frequently exhibits high comorbidity with other psychiatric and somatic disorders. Commonly used treatments, such as selective serotonin reuptake inhibitors (SSRIs), are not ideal since ...
Benjamin Adam, Samuels +8 more
openaire +2 more sources
TREATMENT RESISTANT DEPRESSION
Psychiatry and Clinical Psychopharmacology, 2021 Although it is reported that 25% of depressive patients remain resistant to antidepressant treatments, treatment resistant depression (TRD) has not yet been defined clearly.
Olcay YAZICI
doaj
Esketamine for treatment‑resistant depression: A review of clinical evidence (Review)
Experimental and Therapeutic Medicine, 2023 Treatment-resistant depression (TRD) is a challenge for psychiatrists, even after more than seven decades since the first antidepressants were used in clinical practice.
O. Vasiliu
semanticscholar +1 more source
Rethinking treatment-resistant depression to quasi-tenacious depression
European Psychiatry, 2023 With almost one-third of patients with major depression not adequately responsive to treatments, the management of treatment-resistant depression (TRD) has continued to be challenging.
Shokouh Arjmand +2 more
doaj +1 more source
Annals of General Psychiatry, 2023 Background Treatment-resistant depression (TRD) is defined by the European Medicines Agency as a lack of clinically meaningful improvement after treatment, with at least two different antidepressants.
Giuseppe Maina +61 more
semanticscholar +1 more source
Treatment-resistant depression and its diagnosis and treatment
Sichuan jingshen weisheng, 2022 The aim of this study is to explore the diagnostic strategies and options for treatment-resistant depression （TRD）. Despite the well-established efficacy of antidepressants， 20%~30% of depressive patients in the clinic fail to respond or respond poorly ...
Hu Shaohua
doaj +1 more source
Frontiers in Pharmacology, 2018 Introduction: It is a basic principle of the “psychedelic” treatment model that the quality of the acute experience mediates long-term improvements in mental health.
Leor Roseman, D. Nutt, R. Carhart-Harris
semanticscholar +1 more source
Neuropsychopharmacology, 2021 This study aimed to investigate the role of baseline levels of peripheral inflammation when testing the efficacy of antidepressant augmentation with minocycline in patients with treatment-resistant depression.
M. Nettis +15 more
semanticscholar +1 more source
Metyrapone in treatment-resistant depression [PDF]
Therapeutic Advances in Psychopharmacology, 2012 Depression affects a significant proportion of the population, with 1-year and lifetime prevalence of 3–5% and 10–30% respectively. Full remission is achieved in only a third of patients following treatment with first-line antidepressant. There is a need for novel treatments for treatment-resistant depression (TRD).
Paul David, Sigalas +4 more
openaire +2 more sources