Results 31 to 40 of about 8,080,314 (298)
Opioid agents for treatment-resistant depression
Treatment-resistant depression (TRD) is a major public health problem in terms of prevalence, individual suffering, and cost for society, and it is commonly associated with significant disability and psychosocial impairment worldwide.
Amerio A. +5 more
core +1 more source
Case Report: Use of Subcutaneous Midazolam During an Episode of Catatonia
Midazolam is a benzodiazepine (BZD) mainly used in anesthetic induction due to its pharmacokinetic features. Its place in the therapeutic management of catatonia remains to be determined. Here we present the case of a 65-year-old man who presented with a
Valentin Raymond +5 more
doaj +1 more source
Acceptance and Commitment Therapy group for treatment-resistant participants: a randomized controlled trial [PDF]
Acceptance and Commitment Therapy (ACT) is a theoretically coherent approach addressing common processes across a range of disorders. The aim of this study was to investigate the effectiveness of a group-based ACT intervention for ‘treatment-resistant ...
Clarke, Sue +7 more
core +1 more source
Metyrapone in treatment-resistant depression [PDF]
Depression affects a significant proportion of the population, with 1-year and lifetime prevalence of 3–5% and 10–30% respectively. Full remission is achieved in only a third of patients following treatment with first-line antidepressant. There is a need for novel treatments for treatment-resistant depression (TRD).
Paul David, Sigalas +4 more
openaire +2 more sources
BackgroundPatients with personality disorder (PD) are at risk for suicidal behavior and are frequently admitted for this reason to emergency departments.
Lionel Cailhol +4 more
doaj +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Metacognitive Therapy in Treatment-Resistant Psychosis:A Multiple-Baseline Study [PDF]
Background: More effective psychological treatments for psychosis are required. Case series data and pilot trials suggest metacognitive therapy (MCT) is a promising treatment for anxiety and depression.
Wardle, Melissa +8 more
core +1 more source
A model for the management of difficult to treat depression
In this presentation a model for the management of difficult to treat depression (DTD) will be presented based upon a recently published international consensus statement (McAllister-Williams et al. 2020 Journal of Affective Disorders 267:264-282).
H. Mcallister-Williams
doaj +1 more source
Nortriptyline for Treatment-Resistant Depression [PDF]
Up to 30% of patients with major depression fail to respond to an antidepressant trial, with most taking a selective serotonin reuptake inhibitor (SSRI) as initial treatment. While the tricyclic antidepressants might be effective for SSRI nonresponders, they have been relegated to third- and fourth-line treatment.
Andrew A, Nierenberg +8 more
openaire +2 more sources
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source

