Results 61 to 70 of about 766,404 (301)

Suicidality in Treatment-Resistant Depression Patients

European Psychiatry, 2023
Introduction Depression and treatment-resistant depression (RD) are associated with suicidal behavior (SB) at a higher rate. Objectives 1) determination prevalence of RD in district outpatient psychiatric сlinics (i.e., dispensaries) and the socio ...
E. B. Lyubov, N. D. Semenova
doaj   +1 more source

Patient perspectives and experiences with psilocybin treatment for treatment-resistant depression: a qualitative study

Scientific Reports
Psilocybin is the most researched classic psychedelic for Treatment-Resistant Depression (TRD). While optimizing set and setting are considered essential for efficacy and safety, patient perspectives on these aspects have rarely been investigated.
J. Breeksema, Alistair Niemeijer, E. Krediet, Tilman Karsten, J. Kamphuis, E. Vermetten, Wim van den Brink, Robert Schoevers   +7 more
semanticscholar   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles, Hannah F. Brubeck, Adrienne D. Tanus, Courtney N. Loecker, Punyasha Roul, Bryant R. England, Elizabeth R. Wahl, James S. Andrews, Namrata Singh, Joshua F. Baker, Patricia P. Katz, Dolores M. Shoback, Jose M. Garcia, Ariela R. Orkaby, Katherine D. Wysham   +14 more
wiley   +1 more source

The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression.

Journal of Affective Disorders
OBJECTIVE To determine the relationships between psilocybin dose, psychedelic experiences, and therapeutic outcome in treatment-resistant depression. METHODS For treatment-resistant depression, 233 participants received a single dose of 25, 10, or 1 mg
G. M. Goodwin, S. Aaronson, Oscar Alvarez, Robin Carhart-Harris, Jamie Chai-Rees, M. Croal, C. DeBattista, B. Dunlop, David Feifel, D. Hellerstein, M. I. Husain, John R. Kelly, Namik Kirlić, R. Licht, L. Marwood, Thomas D. Meyer, Sunil Mistry, A. Nowakowska, T. Páleníček, D. Repantis, R. Schoevers, H. Simmons, M. Somers, E. Teoh, J. Tsai, Mourad Wahba, S. Williams, Allan H. Young, Matthew B Young, Sidney Zisook, E. Malievskaia   +30 more
semanticscholar   +1 more source

Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial

Psychological Medicine, 2018
Background Recent open-label trials show that psychedelics, such as ayahuasca, hold promise as fast-onset antidepressants in treatment-resistant depression.
F. Palhano-Fontes, Dayanna Barreto, H. Onias, K. Andrade, Morgana M. Novaes, J. Pessoa, S. Mota-Rolim, F. Osório, R. Sanches, R. G. dos Santos, L. F. Tófoli, Gabriela de Oliveira Silveira, M. Yonamine, J. Riba, F. Santos, Antonio A Silva-Junior, J. Alchieri, N. Galvão-Coelho, B. Lobão-Soares, J. Hallak, Emerson Arcoverde, J. P. Maia-de-Oliveira, D. Araujo   +22 more
semanticscholar   +1 more source

Moderators of the Effects of Exercise and Manual Therapy for People With Knee and Hip Osteoarthritis: A Secondary Analysis of a Randomized Clinical Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate potential moderators influencing the effects of manual therapy and exercise therapy on pain and functional outcomes in individuals with knee and/or hip osteoarthritis, using data from the MOA trial. This is a secondary analysis of data from the MOA trial that compares the clinical effectiveness of manual ...
Daniel Cury Ribeiro, Sarah E. Lamb, J. Haxby Abbott   +2 more
wiley   +1 more source

Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a randomized clinical trial

Molecular Psychiatry
Further research is needed to help improve both the standard of care and the outcome for patients with treatment-resistant depression. A particularly critical evidence gap exists with respect to whether pharmacological or non-pharmacological augmentation
G. Papakostas, Madhukar H. Trivedi, R. Shelton, D. Iosifescu, Michael E. Thase, Manish K. Jha, S. J. Mathew, C. DeBattista, Mehmet e Dokucu, Olga Brawman-Mintzer, Glenn W. Currier, W. V. McCall, M. Modirrousta, Matthew Macaluso, A. Bystritsky, Fidel Vila Rodriguez, Erik B. Nelson, A. Yeung, Anna Feeney, Leslie C. MacGregor, Thomas J. Carmody, M. Fava   +21 more
semanticscholar   +1 more source

Magnitude of the Placebo Response Across Treatment Modalities Used for Treatment-Resistant Depression in Adults

JAMA Network Open, 2021
Key Points Question What is the placebo effect magnitude in different treatment modalities used for management of patients with treatment-resistant depression? Findings In this systematic review and meta-analysis of 3228 patients with treatment-resistant
Brett D. M. Jones, L. Razza, C. Weissman, Jewel Karbi, Tya Vine, Louise S. Mulsant, A. Brunoni, M. Husain, B. Mulsant, D. Blumberger, Z. Daskalakis   +10 more
semanticscholar   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M. Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source

Clinical and biological markers of electroconvulsive therapy effectiveness: a narrative review

Translational Psychiatry
Electroconvulsive therapy (ECT) is the most effective treatment for several particularly severe or pharmacotherapy-resistant psychiatric disorders, and a growing number of studies have investigated factors influencing the effectiveness of ECT.
David Zilles-Wegner, Iven-Alex von Mücke-Heim, Antoine Yrondi, Akihiro Takamiya   +3 more
doaj   +1 more source