Results 71 to 80 of about 5,522 (187)

Newborn Screening Inborn Errors of Immunity in the Republic of Belarus: The First Pilot Study

Journal of Human Immunity
Background and AimsThe primary focus of neonatal screening is the early detection of asymptomatic infants with a range of serious diseases for which effective treatment is available and for which early diagnosis and intervention will prevent serious ...
E.A. Polyakova, T.P. Volodashchik, O.L. Zobikova, A.V. Liubushkin, E.A. Kalinina, S.A. Aleshkevich, Yu.S. Zharankova, I.S. Sakovich, A.N. Kupchinskaya, I.E. Guryanova, O.V. Pribushenya, S.O. Sharapova, M.V. Belevtsev, A.V. Solntsava   +13 more
doaj   +1 more source

Effect of repeated hot water immersion on muscle strength, power, function and physical activity in healthy older adults: A randomised crossover trial

Experimental Physiology, EarlyView.
Abstract Ageing leads to an increased prevalence of sarcopenia and frailty, characterised by progressive declines in muscle strength, power and function and reduced physical activity. Hot water immersion (HWI) could potentially improve muscle function, but this is yet to be explored in older adults.
Daniel D. Piccolo, Jo Corbett, Timothy A. Exell, Joseph M. Moore, Amy Wright, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +12 more
wiley   +1 more source

The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases

Immunological Medicine
T cell receptor rearrangement excision circles (TRECs) and immunoglobulin κ-deleting recombination excision circles (KRECs) represent the lymphopoiesis capacity, widely used for newborn screening of inborn errors of immunity.
Takuji Itakura, Hirokazu Sasaki, Tadashi Hosoya, Natsuka Umezawa, Tetsuya Saito, Hideyuki Iwai, Hisanori Hasegawa, Hiroyuki Sato, Akihiro Hirakawa, Kohsuke Imai, Tomohiro Morio, Naoki Kimura, Shinsuke Yasuda   +12 more
doaj   +1 more source

DETERMINATION OF REFERENCE VALUES FOR TREC AND KREC IN DRY BLOOD SPOTS OF NEWBORNS FROM DIFFERENT GESTATION AGES IN SVERDLOVSK REGION

Медицинская иммунология, 2018
As a preparatory stage for implementation of genetic testing for severe combined immunodeficiency under a neonatal screening program, a study was performed in Sverdlovsk Region which concerned quantitative determination of T and B cell neogenesis markers
S. S. Deryabina, I. A. Tuzankina, V. N. Shershnev   +2 more
doaj   +1 more source

Far‐infrared sauna exposure at 65°C elevates core temperature

Experimental Physiology, EarlyView.
Abstract Far‐infrared (FIR) saunas are increasingly used as a passive heating and ‘wellness’ modality, yet their capacity to elevate core temperature remains unclear, particularly given prior work at lower temperatures (∼45°C) reports limited net heat storage.
Elliott J. Jenkins, Joseph A. Killick, Sally R. Grimm, Sam R. Davies, Jemima A. Benson, Joshua C. Tremblay, Mike Stembridge   +6 more
wiley   +1 more source

V(D)J Recombination Excision Circles of B- and T-cells as Prognostic Marker in B-Cell Chronic Lymphocytic Leukemia

Клиническая онкогематология, 2017
Background & Aims. T-cell receptor excision circles (TREC) and κ-deleting recombination excision circles (KREC) are extrachromosomal DNA segments generated during V(D)J re combination process that characterize the diversity of the antigen repertoire of T-
Igor’ Vladimirovich Obraztsov, M. A. Gordukova, N. A. Severina, B. V. Biderman, S. Yu. Smirnova, A. B. Sudarikov, E. A. Nikitin, A. G. Rumyantsev   +7 more
doaj   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins, Phuong L. Ha, Connor A. Howe, Jay M. J. R. Carr, Justin A. Monteleone, Andrew J. M. Douglas, Abigail Nicholson, Andrew Steele, Brydie Lemkes, Jodie L. Koep, L. Madden Brewster, Jennifer Duffy, Mathew I. B. Debenham, Tena Monaghan, Declan Isaak, Jacob McCormick, Brian H. Dalton, Chris J. McNeil, Jared Baylis, David MacLeod, Mike Stembridge, Markus Amann, Philip N. Ainslie, Travis D. Gibbons   +23 more
wiley   +1 more source

Review on Recent Advances in Conducting Polymer/Metal‐Oxide Nanocomposite Chemiresistors for Environmental Gas Monitoring

Macromolecular Materials and Engineering, Volume 311, Issue 8, August 2026.
Conducting polymer/metal‐oxide nanocomposites emerge as highly promising chemiresistive sensing materials for environmental gas monitoring. Recent advances reveal strong synergistic effects that enhance sensitivity, selectivity, stability, and response kinetics while enabling lower‐temperature operation.
Katekani Shingange, Sivuyisiwe Mapukata, Teboho Mokhena, Thandi Patricia Gumede, David Rogers, Martin Ntwaeaborwa   +5 more
wiley   +1 more source

Aligning Real‐Time Recurrence Computational Fluid Dynamics Simulations with Plant Data for the Ruhrstahl–Heraeus Degassing Process of Steel

steel research international, Volume 97, Issue 8, Page 4207-4222, August 2026.
Uncertainties exist in computational fluid dynamics (CFD) modeling of complex metallurgical processes, even when partly validated by laboratory experiments. rCFD enables computationally efficient prediction of long‐term RH degassing and can be adapted to vary flow conditions.
Xiaomeng Zhang, Maria Thumfart, Roman Rössler, Stefan Pirker   +3 more
wiley   +1 more source

TITAN‐LSTM: A Weather Radar Nowcasting Tool

Journal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 4, August 2026.
Abstract Precipitation nowcasting is essential for a wide range of meteorological and hydrological applications, and weather radar plays a central role in this task. Extrapolation algorithms such as TITAN (Thunderstorm Identification, Tracking, Analysis and Nowcasting) provide efficient storm tracking but do not directly use rainfall rate fields, while
Andrea S. Viteri López, Carlos A. Morales Rodriguez   +1 more
wiley   +1 more source