Results 21 to 30 of about 20,481 (222)

Genome of the Chinese tree shrew [PDF]

Nature Communications, 2013
Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as models for a variety of human disorders: depression, myopia, hepatitis B and C virus infections, and hepatocellular carcinoma, to name a few.
Fan, Yu, Huang, Zhi-Yong, Cao, Chang-Chang, Chen, Ce-Shi, Chen, Yuan-Xin, Fan, Ding-Ding, He, Jing, Hou, Hao-Long, Hu, Li, Hu, Xin-Tian, Jiang, Xuan-Ting, Lai, Ren, Lang, Yong-Shan, Liang, Bin, Liao, Sheng-Guang, Mu, Dan, Ma, Yuan-Ye, Niu, Yu-Yu, Sun, Xiao-Qing, Xia, Jin-Quan, Xiao, Jin, Xiong, Zhi-Qiang, Xu, Lin, Yang, Lan, Zhang, Yun, Zhao, Wei, Zhao, Xu-Dong, Zheng, Yong-Tang, Zhou, Ju-Min, Zhu, Ya-Bing, Zhang, Guo-Jie, Wang, Jun, Yao, Yong-Gang   +32 more
openaire   +4 more sources

Drug target mining and analysis of the Chinese tree shrew for pharmacological testing. [PDF]

PLoS ONE, 2014
The discovery of new drugs requires the development of improved animal models for drug testing. The Chinese tree shrew is considered to be a realistic candidate model.
Feng Zhao, Xiaolong Guo, Yanjie Wang, Jie Liu, Wen-hui Lee, Yun Zhang   +5 more
doaj   +1 more source

Comparative Anatomy and Histology of Elephant, Human, and Tree Shrew Brains

Biomedical Sciences and Clinical Medicine, 2022
OBJECTIVE This study was designed to compare elephant brain mor-phology and histology with that of humans and tree shrews.METHODS The size of elephant, human, and tree shrew brains were measured.
Noppadol Phasukdee, Kewalee Seeharach, Chaleamchat Somgird, Taweepoke Angkavanish, Anucha Sathanawongs, Sittidet Mahasawangkul, Chatchote Thitaram, Ranida Quiggins   +7 more
doaj   +1 more source

Revealing histological and morphological features of female reproductive system in tree shrew (Tupaia belangeri) [PDF]

, 2018
The tree shrew has been used as a primate animal model in neuroscience studies but it has only rarely been employed in the study of reproductive systems. This is mainly because we know very little about the histological features of reproductive organs of
D Dixon, D Emerson, D Glebe, D Yu, DF Lazarous, E Zappi, Guang Wang, H Fang, Hui-jie Xing, J Cao, J Hu, J Nair, Jiang-nan Fu, L Ye, L Zhang, M Ezzati, M Manohar, N Kawano, P Coy, S Zhang, Shan Zhong, Shi-yao Zhang, SM Hawkins, TE Spencer, XH Pan, Xiao-tan Zhang, Xuesong Yang, Y Fan, Y Fan, Y Feng, Y Li, Yong-ping Bao   +31 more
core   +1 more source

The characteristics of gut microbiota and commensal Enterobacteriaceae isolates in tree shrew (Tupaia belangeri)

BMC Microbiology, 2019
Background Tree shrew is a novel laboratory animal with specific characters for human disease researches in recent years. However, little is known about its characteristics of gut microbial community and intestinal commensal bacteria.
Wenpeng Gu, Pinfen Tong, Chenxiu Liu, Wenguang Wang, Caixia Lu, Yuanyuan Han, Xiaomei Sun, De Xuan Kuang, Na Li, Jiejie Dai   +9 more
doaj   +1 more source

Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia

Virology Journal, 2020
Background Following acute infection, Herpes Simplex virus-1 (HSV-1) establishes lifelong latency and recurrent reactivation in the sensory neurons of trigeminal ganglia (TG).
Erlin Wang, Yunshuang Ye, Ke Zhang, Jinlong Yang, Daohua Gong, Jianhua Zhang, Renjun Hong, Huan Zhang, Lihong Li, Guijun Chen, Liping Yang, Jianmei Liu, Hanyu Cao, Ting Du, Nigel W. Fraser, Le Cheng, Xia Cao, Jumin Zhou   +17 more
doaj   +1 more source

Coalescent-based genome analyses resolve the early branches of the euarchontoglires [PDF]

, 2013
Despite numerous large-scale phylogenomic studies, certain parts of the mammalian tree are extraordinarily difficult to resolve. We used the coding regions from 19 completely sequenced genomes to study the relationships within the super-clade ...
A Criscuolo, Axel Janke, B Rannala, Björn M. Hallström, BM Hallström, BM Hallström, BM Hallström, BM Hallström, C Lanave, CA Russo, D Curnoe, DE Pumo, DE Wildman, DH Huson, G Churakov, G Jobb, H Shimodaira, H Shimodaira, Hans Ellegren, J Schmitz, JA van Dam, JC Avise, JE Janecka, JE McCormack, JFC Kingman, JH Degnan, JJ Fong, JO Kriegs, JP Townsend, K Katoh, KM Kjer, L Liu, L Liu, L Liu, LS Kubatko, M Dos Reis, MJ Novacek, MP Simmons, NM Jameson, PJ Waddell, RJ Asher, S Guindon, S Kumar, S Song, S Whelan, SV Edwards, TH Ogden, TK Seo, U Arnason, U Arnason, Vikas Kumar, WJ Murphy, WP Maddison   +52 more
core   +3 more sources

Predation by Amphibians and Small Mammals on the Spruce Budworm (Lepidoptera: Tortricidae) [PDF]

, 2017
Stomach-content analyses of pitfall-trapped amphibians and small mammals showed that the eastern American toad, Bujo americanus americanus, and the wood frog, Rana sylvatica, preyed on late instars and moths of the spruce budworm, Choristoneura ...
Crawford, Hewlette S, Jr., Hunter, Malcolm L, Jr., Jennings, Daniel T   +2 more
core   +2 more sources

Autophagy Induction by HIV-Tat and Methamphetamine in Primary Midbrain Neuronal Cells of Tree Shrews via the mTOR Signaling and ATG5/ATG7 Pathway

Frontiers in Neuroscience, 2018
Background: Addictive stimulant drugs, such as methamphetamine (METH), increase the risk of exposure to the human immunodeficiency virus-1 (HIV-1) infection and thus predispose individuals to the development of HIV-associated neurocognitive disorders ...
Juan Li, Juan Li, Wenguang Wang, Pinfen Tong, Chi-Kwan Leung, Chi-Kwan Leung, Genmeng Yang, Zhen Li, Na Li, Xiaomei Sun, Yuanyuan Han, Caixia Lu, Dexuan Kuang, Jiejie Dai, Xiaofeng Zeng   +14 more
doaj   +1 more source

Tree Shrew as an Emerging Small Animal Model for Human Viral Infection: A Recent Overview

Viruses, 2021
Viral infection is a global public health threat causing millions of deaths. A suitable small animal model is essential for viral pathogenesis and host response studies that could be used in antiviral and vaccine development.
Mohammad Enamul Hoque Kayesh, Takahiro Sanada, Michinori Kohara, Kyoko Tsukiyama-Kohara   +3 more
doaj   +1 more source