Identification of glyceraldehyde 3-phosphate dehydrogenase sequence and expression profiles in tree shrew (Tupaia belangeri). [PDF]
PLoS ONE, 2014 The tree shrews (Tupaia belangeri) diverged from the primate order (Primates) and are classified as Scandentia, a separate taxonomic group of mammals.
Yu Zheng +5 more
doaj +1 more source
BMC Microbiology, 2020 Background Clostridioides difficile is a major cause of antibiotic associated diarrhea. Several animal models are used to study C. difficile infection (CDI). The tree shrew has recently been developed as a model of primate processes. C.
Wenpeng Gu +12 more
doaj +1 more source
A Novel Tree Shrew Model of Diabetic Retinopathy. [PDF]
Front Endocrinol (Lausanne), 2021 Existing animal models with rod-dominant retinas have shown that hyperglycemia injures neurons, but it is not yet clearly understood how blue cone photoreceptors and retinal ganglion cells (RGCs) deteriorate in patients because of compromised insulin tolerance. In contrast, northern tree shrews (Tupaia Belangeri), one of the closest living relatives of
Gorbatyuk OS +8 more
europepmc +5 more sources
CXC chemokine CXCL12 and its receptor CXCR4 in tree shrews (Tupaia belangeri): structure, expression and function. [PDF]
PLoS ONE, 2014 Chemokines are small secreted proteins functionally involved in the immune system's regulation of lymphocyte migration across numerous mammalian species.
Guiyuan Chen +8 more
doaj +1 more source
Identification of PDK4 as Hub Gene for Diabetic Nephropathy Using Co-Expression Network Analysis
Kidney & Blood Pressure Research, 2023 Introduction: Diabetic nephropathy (DN) is related to type 1 and type 2 diabetes. They are the leading cause of end-stage renal disease, but the underling specific pathogenesis of DN is not yet clear. Our study was conducted to explore how DN changed the
Yuanyuan Han +4 more
doaj +1 more source
Anatomy and nomenclature of tree shrew lymphoid tissues. [PDF]
Exp Anim, 2022 The immune response plays a key role in the disease development of the organism, while immune function serves as an important indicator for animal models evaluation. The tree shrew (Tupaia belangeri chinensis), as a new laboratory animal with a close genetic relationship with primates, has been used to construct various disease models.
Shi N +6 more
europepmc +4 more sources
Drug target mining and analysis of the Chinese tree shrew for pharmacological testing. [PDF]
PLoS ONE, 2014 The discovery of new drugs requires the development of improved animal models for drug testing. The Chinese tree shrew is considered to be a realistic candidate model.
Feng Zhao +5 more
doaj +1 more source
Comparative Anatomy and Histology of Elephant, Human, and Tree Shrew Brains
Biomedical Sciences and Clinical Medicine, 2022 OBJECTIVE This study was designed to compare elephant brain mor-phology and histology with that of humans and tree shrews.METHODS The size of elephant, human, and tree shrew brains were measured.
Noppadol Phasukdee +7 more
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Revealing histological and morphological features of female reproductive system in tree shrew (Tupaia belangeri) [PDF]
, 2018 The tree shrew has been used as a primate animal model in neuroscience studies but it has only rarely been employed in the study of reproductive systems. This is mainly because we know very little about the histological features of reproductive organs of
D Dixon +31 more
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BMC Microbiology, 2019 Background Tree shrew is a novel laboratory animal with specific characters for human disease researches in recent years. However, little is known about its characteristics of gut microbial community and intestinal commensal bacteria.
Wenpeng Gu +9 more
doaj +1 more source