Results 11 to 20 of about 4,894 (199)

The Tree Shrew as a Model for Cancer Research [PDF]

open access: yesFrontiers in Oncology, 2021
Animal disease models are necessary in medical research, and an appropriate animal model is of great importance for studies about the prevention or treatment of cancer.
Tao Lu   +6 more
doaj   +3 more sources

Nerve growth factor promotes in vitro proliferation of neural stem cells from tree shrews

open access: yesNeural Regeneration Research, 2016
Neural stem cells promote neuronal regeneration and repair of brain tissue after injury, but have limited resources and proliferative ability in vivo.
Liu-lin Xiong   +2 more
doaj   +2 more sources

Response of the gut microbiota during the Clostridioides difficile infection in tree shrews mimics those in humans [PDF]

open access: yesBMC Microbiology, 2020
Background Clostridioides difficile is a major cause of antibiotic associated diarrhea. Several animal models are used to study C. difficile infection (CDI). The tree shrew has recently been developed as a model of primate processes. C.
Wenpeng Gu   +12 more
doaj   +2 more sources

Washed Microbiota Transplantation Accelerates the Recovery of Abnormal Changes by Light-Induced Stress in Tree Shrews [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The gut and brain interact constantly in a complex fashion. Its intricacy and intrigue is progressively being revealed in the study of the “gut–brain axis”.
Jing Wang   +14 more
doaj   +2 more sources

CXC chemokine CXCL12 and its receptor CXCR4 in tree shrews (Tupaia belangeri): structure, expression and function. [PDF]

open access: yesPLoS ONE, 2014
Chemokines are small secreted proteins functionally involved in the immune system's regulation of lymphocyte migration across numerous mammalian species.
Guiyuan Chen   +8 more
doaj   +2 more sources

Experimental chronic hepatitis B infection of neonatal tree shrews (Tupaia belangeri chinensis): A model to study molecular causes for susceptibility and disease progression to chronic hepatitis in humans

open access: yesVirology Journal, 2012
Background Hepatitis B virus (HBV) infection continues to be an escalating global health problem. Feasible and effective animal models for HBV infection are the prerequisite for developing novel therapies for this disease.
Wang Qi   +15 more
doaj   +2 more sources

Comparative genomic analysis of Proteus spp. isolated from tree shrews indicated unexpectedly high genetic diversity.

open access: yesPLoS ONE, 2020
Proteus spp. are commensal gastrointestinal bacteria in many hosts, but information regarding the mutual relationships between these bacteria and their hosts is limited.
Wenpeng Gu   +10 more
doaj   +2 more sources

Tree shrews (tupaia belangeri) exhibit novelty preference in the novel location memory task with 24-hour retention periods.

open access: yesFrontiers in Psychology, 2014
Novelty preference is pervasive in mammalian species, and describes an inherent tendency to preferentially explore novelty. The novel location memory task studied here assesses the ability of animals to form accurate memories of a spatial configuration,
Jayakrishnan H R Nair   +8 more
doaj   +2 more sources

Depression-like behaviors in tree shrews and comparison of the effects of treatment with fluoxetine and carbetocin

open access: yesPharmacology Biochemistry and Behavior, 2016
Tree shrews, a species phylogenetically close to primates, are regarded as a suitable and naturalistic animal model for depression studies. However, psychological symptoms that are essential for depression diagnosis and treatment, such as helplessness ...
Xiaolu Meng, Fang Shen, Chunlu Li
exaly   +2 more sources

Pulmonary histiocytosis in tree shrews (Tupaia belangeri)

open access: yesLaboratory animal science, 1997
Granulomatous lesions similar to those of pulmonary histiocytosis in rats developed spontaneously in the lungs of captive tree shrews. Incidence peaked in 3-year-old tree shrews.
Brack, M.   +4 more
core   +4 more sources

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