Results 21 to 30 of about 4,894 (199)
Body surface area-based equivalent dose calculation in tree shrew
Science Progress, 2021 Tree shrew (Tupaia belangeri) is a promising experimental animal in biomedical research, but the equivalent doses of drugs between tree shrew and human and other animals has not been explored, which hinders its further application in a wider scope.
Wei Xia +4 more
doaj +1 more source
COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2 [PDF]
Zoological Research, 2020 Ling Xu, Dan-Dan Yu, Yu-Hua Ma
exaly +2 more sources
Frontiers in Microbiology, 2021 Kaposi’s sarcoma-associated herpesvirus (KSHV) is the most common cause of Kaposi’s sarcoma (KS) and other malignant growths in humans. However, the lack of a KSHV-infected small animal model has hampered understanding of the mechanisms of KSHV infection,
Daoqun Li +9 more
doaj +1 more source
Genome of the Chinese tree shrew [PDF]
Nature Communications, 2013 Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as models for a variety of human disorders: depression, myopia, hepatitis B and C virus infections, and hepatocellular carcinoma, to name a few.
Fan, Yu +32 more
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Involvement of dopamine D3 receptor and dopamine transporter in methamphetamine‐induced behavioral sensitization in tree shrews [PDF]
Brain and Behavior, 2020 Genmeng Yang +2 more
exaly +2 more sources
Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew [PDF]
Scientific Reports, 2014 The tree shrew (Tupaia belangeri) is a small mammal with a close relationship to primates and it has been proposed as an alternative experimental animal to primates in biomedical research. The recent release of a high-quality Chinese tree shrew genome enables more researchers to use this species as the model animal in their studies.
Yu Fan, Dandan Yu, Yong-Gang Yao
openaire +2 more sources
A Novel Tree Shrew Model of Chronic Experimental Autoimmune Uveitis and Its Disruptive Application
Frontiers in Immunology, 2022 BackgroundPrevious studies have established several animal models for experimental autoimmune uveitis (EAU) in rodents without the fovea centralis in the human retina.
Kaijiao Hu +19 more
doaj +1 more source
The Second Visual System of The Tree Shrew [PDF]
Journal of Comparative Neurology, 2018 Abstract This review provides a historical account of the discovery of secondary visual pathways (from retina to the superior colliculus to the dorsal thalamus and extrastriate cortex), and Vivien Casagrande's pioneering studies of this system using the tree shrew as a model. Subsequent studies of visual pathways in the tree shrew are
Heywood M. Petry, Martha E. Bickford
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A study of Epstein-Barr virus infection in the Chinese tree shrew(Tupaia belangeri chinensis)
Virology Journal, 2017 Background Epstein–Barr virus (EBV) is closely associated with many human diseases, including a variety of deadly human malignant tumours. However, due to the lack of ideal animal models,the biological characteristics of EBV, particularly its function in
Zhi Wang +10 more
doaj +1 more source
Tree Shrew as a New Animal Model for the Study of Dengue Virus
Frontiers in Immunology, 2021 Dengue virus is a significant public health threat worldwide; however, the pathogenesis of dengue disease remains poorly understood due to lack of appropriate small animal models.
Liming Jiang +6 more
doaj +1 more source