Results 311 to 320 of about 275,584 (397)

Pharmacokinetics of Therapeutic Tregs

American Journal of Transplantation, 2014
openaire   +2 more sources

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Predictive value of Th17/Treg immune imbalance for disease severity and poor prognosis in children with respiratory syncytial virus pneumonia. [PDF]

Front Pediatr
Zhu M, Liu J.
europepmc   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source

SIRT3-SUMO regulated Treg cell differentiation and asthma development by mediating N-glycosylation through the FAO pathway. [PDF]

Cell Biol Toxicol
Hu Y, Liu C.
europepmc   +1 more source

Immunomodulatory Fibrous Scaffold with Dual Enzyme‐Mimic Activities Prevents Postsurgical Tumor Recurrence

Advanced Science, EarlyView.
A MnOx nanozyme‐functionalized electrospun fibrous scaffold is developed for postoperative therapy by leveraging its intrinsic physicochemical and immunomodulatory properties. Integrating POD‐ and CAT‐like activities, the scaffold induces immunogenic cell death, alleviates hypoxia, and reverses immunosuppression, while simultaneously recruiting and ...
Xiaoyi Zhao, Zhuolong Jiao, Yue Wang, Huimeng Gu, Longfei Li, Jian Song, Chen Xu, Jiajia Xue, Fu‐Jian Xu, Nana Zhao   +9 more
wiley   +1 more source

Irisin-Treg crosstalk: unveiling a mechanism in neural cognitive regulation. [PDF]

Ann Med
Zhan R, Yang J, Wan Q, Zhang J, Liu L, Jiang J, Mo L, Bai Y.   +7 more
europepmc   +1 more source

Interleukin-10 Producing Regulatory B Cells Transformed CD4+CD25− Into Tregs and Enhanced Regulatory T Cells Function in Human Leprosy

, 2018
Mohammad Tarique, Huma Naz, Santosh Kurra, Chaman Saini, Raza Ali Naqvi, Reeta Rai, Mohd Suhail, Neena Khanna, D. N. Rao, Alpana Sharma   +9 more
openalex   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Longitudinal immune profiling uncovers regulatory T cell signatures associated with the progression of COVID-19. [PDF]

Front Immunol
Kossack C, Bravo F, Fuentes-Villalobos F, Quevedo C, Medina MA, Riquelme R, Rioseco ML, Calvo M, Pino-Lagos K, Aguilera F, Barría MI, Garrido JL.   +11 more
europepmc   +1 more source